KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC8
All Species:
20.61
Human Site:
S616
Identified Species:
45.33
UniProt:
Q09428
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09428
NP_000343.2
1581
177008
S616
K
L
S
E
F
L
S
S
A
E
I
R
E
E
Q
Chimpanzee
Pan troglodytes
XP_508310
1551
173975
S586
K
L
S
E
F
L
S
S
A
E
I
R
E
E
Q
Rhesus Macaque
Macaca mulatta
XP_001088694
1581
176783
S616
K
L
S
E
F
L
S
S
A
E
I
R
E
E
Q
Dog
Lupus familis
XP_542520
1543
172550
S616
K
L
S
E
F
L
S
S
A
E
I
R
E
E
Q
Cat
Felis silvestris
Mouse
Mus musculus
P70170
1546
174220
N604
I
I
S
V
Q
K
L
N
E
F
L
L
S
D
E
Rat
Rattus norvegicus
Q09429
1582
177166
S616
K
L
S
E
F
L
S
S
A
E
I
R
E
E
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F364
1525
170953
P556
T
F
T
W
V
C
A
P
F
L
V
A
L
S
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166118
1581
177105
C616
K
L
S
E
F
F
S
C
D
E
I
G
G
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
S381
R
V
E
Q
F
M
Q
S
E
E
L
G
S
S
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7GB25
1514
168556
G554
F
A
T
S
I
F
L
G
T
Q
L
T
A
G
G
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
F548
F
L
V
S
C
C
T
F
A
V
F
V
Y
T
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.4
92.7
N.A.
67.3
95.6
N.A.
N.A.
31.8
N.A.
76.2
N.A.
29.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.9
94.6
N.A.
79.9
97.1
N.A.
N.A.
52
N.A.
85.1
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
100
N.A.
N.A.
0
N.A.
66.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
40
100
N.A.
N.A.
20
N.A.
66.6
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.9
52.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
10
0
55
0
0
10
10
0
0
% A
% Cys:
0
0
0
0
10
19
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% D
% Glu:
0
0
10
55
0
0
0
0
19
64
0
0
46
55
19
% E
% Phe:
19
10
0
0
64
19
0
10
10
10
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
19
10
10
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
10
0
0
10
0
0
0
0
0
55
0
0
0
0
% I
% Lys:
55
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
64
0
0
0
46
19
0
0
10
28
10
10
0
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
0
10
0
0
10
0
0
0
0
55
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
46
0
0
0
% R
% Ser:
0
0
64
19
0
0
55
55
0
0
0
0
19
19
0
% S
% Thr:
10
0
19
0
0
0
10
0
10
0
0
10
0
10
10
% T
% Val:
0
10
10
10
10
0
0
0
0
10
10
10
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _