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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ABCC8 All Species: 18.18
Human Site: T1320 Identified Species: 40
UniProt: Q09428 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q09428 NP_000343.2 1581 177008 T1320 R I H G L L K T E A E S Y E G
Chimpanzee Pan troglodytes XP_508310 1551 173975 T1290 R I H G L L K T E A E S Y E G
Rhesus Macaque Macaca mulatta XP_001088694 1581 176783 T1320 R I H G L L K T E A E S Y E G
Dog Lupus familis XP_542520 1543 172550 L1308 L A D M E I Q L G A V K R I H
Cat Felis silvestris
Mouse Mus musculus P70170 1546 174220 S1287 N S F L T M E S E N Y E G T M
Rat Rattus norvegicus Q09429 1582 177166 T1321 R I H T L L K T E A E S Y E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5F364 1525 170953 K1266 K E Y A E M E K E A E W S I E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001166118 1581 177105 T1320 R I K A L L R T E P E N Y E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P91660 1290 143990 F1058 N V L K S L S F V I Q P R E K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7GB25 1514 168556 I1239 K I I S I E R I Y Q Y S Q I V
Baker's Yeast Sacchar. cerevisiae P39109 1515 171103 I1243 N I V S V E R I K E Y A D L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.9 98.4 92.7 N.A. 67.3 95.6 N.A. N.A. 31.8 N.A. 76.2 N.A. 29.4 N.A. N.A. N.A.
Protein Similarity: 100 97.3 98.9 94.6 N.A. 79.9 97.1 N.A. N.A. 52 N.A. 85.1 N.A. 46.8 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 6.6 93.3 N.A. N.A. 20 N.A. 66.6 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 26.6 93.3 N.A. N.A. 46.6 N.A. 80 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.4 29.6 N.A.
Protein Similarity: N.A. N.A. N.A. 51.9 52.3 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 19 0 0 0 0 0 55 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % D
% Glu: 0 10 0 0 19 19 19 0 64 10 55 10 0 55 10 % E
% Phe: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 28 0 0 0 0 10 0 0 0 10 0 46 % G
% His: 0 0 37 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 64 10 0 10 10 0 19 0 10 0 0 0 28 0 % I
% Lys: 19 0 10 10 0 0 37 10 10 0 0 10 0 0 19 % K
% Leu: 10 0 10 10 46 55 0 10 0 0 0 0 0 10 0 % L
% Met: 0 0 0 10 0 19 0 0 0 0 0 0 0 0 10 % M
% Asn: 28 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 0 0 10 10 0 10 0 0 % Q
% Arg: 46 0 0 0 0 0 28 0 0 0 0 0 19 0 0 % R
% Ser: 0 10 0 19 10 0 10 10 0 0 0 46 10 0 0 % S
% Thr: 0 0 0 10 10 0 0 46 0 0 0 0 0 10 0 % T
% Val: 0 10 10 0 10 0 0 0 10 0 10 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 10 0 28 0 46 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _