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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC8
All Species:
25.15
Human Site:
T261
Identified Species:
55.33
UniProt:
Q09428
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09428
NP_000343.2
1581
177008
T261
P
I
A
M
R
A
L
T
N
Y
Q
R
L
C
E
Chimpanzee
Pan troglodytes
XP_508310
1551
173975
T231
P
I
A
M
R
A
L
T
N
Y
Q
R
L
C
E
Rhesus Macaque
Macaca mulatta
XP_001088694
1581
176783
T261
P
I
A
M
R
A
L
T
N
Y
Q
R
L
R
E
Dog
Lupus familis
XP_542520
1543
172550
T261
P
I
A
M
R
A
L
T
N
Y
Q
R
L
C
E
Cat
Felis silvestris
Mouse
Mus musculus
P70170
1546
174220
T259
P
I
A
M
R
A
V
T
N
Y
V
C
L
K
E
Rat
Rattus norvegicus
Q09429
1582
177166
T261
P
I
A
M
R
A
L
T
N
Y
Q
R
L
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F364
1525
170953
Q230
W
I
T
G
L
M
I
Q
G
H
R
R
P
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166118
1581
177105
T261
P
I
A
M
R
A
L
T
N
Y
I
K
L
R
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
E62
L
C
A
S
W
E
R
E
L
K
N
D
G
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7GB25
1514
168556
G234
V
T
P
Y
S
T
A
G
L
V
S
L
I
T
L
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
L229
T
F
S
W
M
S
G
L
M
K
T
G
Y
E
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.4
92.7
N.A.
67.3
95.6
N.A.
N.A.
31.8
N.A.
76.2
N.A.
29.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.9
94.6
N.A.
79.9
97.1
N.A.
N.A.
52
N.A.
85.1
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
100
N.A.
73.3
93.3
N.A.
N.A.
20
N.A.
73.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
100
N.A.
80
93.3
N.A.
N.A.
40
N.A.
86.6
N.A.
6.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.9
52.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
73
0
0
64
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
10
0
37
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
10
0
0
0
0
0
10
55
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
10
10
0
0
10
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
73
0
0
0
0
10
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
19
0
10
0
10
10
% K
% Leu:
10
0
0
0
10
0
55
10
19
0
0
10
64
10
19
% L
% Met:
0
0
0
64
10
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
64
0
10
0
0
0
0
% N
% Pro:
64
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
46
0
0
0
10
% Q
% Arg:
0
0
0
0
64
0
10
0
0
0
10
55
0
28
0
% R
% Ser:
0
0
10
10
10
10
0
0
0
0
10
0
0
0
10
% S
% Thr:
10
10
10
0
0
10
0
64
0
0
10
0
0
10
0
% T
% Val:
10
0
0
0
0
0
10
0
0
10
10
0
0
0
0
% V
% Trp:
10
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
64
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _