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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC8
All Species:
20
Human Site:
Y1325
Identified Species:
44
UniProt:
Q09428
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09428
NP_000343.2
1581
177008
Y1325
L
K
T
E
A
E
S
Y
E
G
L
L
A
P
S
Chimpanzee
Pan troglodytes
XP_508310
1551
173975
Y1295
L
K
T
E
A
E
S
Y
E
G
L
L
A
P
S
Rhesus Macaque
Macaca mulatta
XP_001088694
1581
176783
Y1325
L
K
T
E
A
E
S
Y
E
G
L
L
A
P
S
Dog
Lupus familis
XP_542520
1543
172550
R1313
I
Q
L
G
A
V
K
R
I
H
G
L
L
K
T
Cat
Felis silvestris
Mouse
Mus musculus
P70170
1546
174220
G1292
M
E
S
E
N
Y
E
G
T
M
D
P
S
Q
V
Rat
Rattus norvegicus
Q09429
1582
177166
Y1326
L
K
T
E
A
E
S
Y
E
G
L
L
A
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F364
1525
170953
S1271
M
E
K
E
A
E
W
S
I
E
E
T
A
P
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166118
1581
177105
Y1325
L
R
T
E
P
E
N
Y
E
G
L
L
S
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
R1063
L
S
F
V
I
Q
P
R
E
K
V
G
I
V
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7GB25
1514
168556
Q1244
E
R
I
Y
Q
Y
S
Q
I
V
G
E
A
P
A
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
D1248
E
R
I
K
E
Y
A
D
L
K
S
E
A
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.4
92.7
N.A.
67.3
95.6
N.A.
N.A.
31.8
N.A.
76.2
N.A.
29.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.9
94.6
N.A.
79.9
97.1
N.A.
N.A.
52
N.A.
85.1
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
6.6
100
N.A.
N.A.
33.3
N.A.
66.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
100
N.A.
N.A.
53.3
N.A.
86.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.9
52.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
55
0
10
0
0
0
0
0
64
10
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
19
19
0
64
10
55
10
0
55
10
10
19
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
0
46
19
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
19
0
10
0
0
0
28
0
0
0
10
0
0
% I
% Lys:
0
37
10
10
0
0
10
0
0
19
0
0
0
10
0
% K
% Leu:
55
0
10
0
0
0
0
0
10
0
46
55
10
0
10
% L
% Met:
19
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
10
0
0
0
0
10
0
64
0
% P
% Gln:
0
10
0
0
10
10
0
10
0
0
0
0
0
10
0
% Q
% Arg:
0
28
0
0
0
0
0
19
0
0
0
0
0
0
0
% R
% Ser:
0
10
10
0
0
0
46
10
0
0
10
0
19
0
46
% S
% Thr:
0
0
46
0
0
0
0
0
10
0
0
10
0
0
10
% T
% Val:
0
0
0
10
0
10
0
0
0
10
10
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
28
0
46
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _