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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCC8
All Species:
17.88
Human Site:
Y15
Identified Species:
39.33
UniProt:
Q09428
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09428
NP_000343.2
1581
177008
Y15
S
E
N
H
S
A
A
Y
R
V
D
Q
G
V
L
Chimpanzee
Pan troglodytes
XP_508310
1551
173975
V15
L
L
A
L
T
G
E
V
L
L
W
P
R
W
G
Rhesus Macaque
Macaca mulatta
XP_001088694
1581
176783
Y15
S
E
N
H
S
A
A
Y
R
V
D
Q
G
V
L
Dog
Lupus familis
XP_542520
1543
172550
Y15
S
E
N
R
S
A
A
Y
R
V
D
Q
G
V
L
Cat
Felis silvestris
Mouse
Mus musculus
P70170
1546
174220
I15
N
N
I
S
S
Y
N
I
Y
Y
G
V
L
Q
N
Rat
Rattus norvegicus
Q09429
1582
177166
Y15
T
E
N
H
S
A
A
Y
R
V
D
Q
G
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F364
1525
170953
F15
S
A
D
A
S
E
P
F
W
D
W
N
L
T
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001166118
1581
177105
Y15
N
D
N
N
S
A
A
Y
N
V
D
A
G
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91660
1290
143990
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q7GB25
1514
168556
E18
R
E
H
L
P
L
L
E
L
C
S
V
I
I
N
Baker's Yeast
Sacchar. cerevisiae
P39109
1515
171103
S15
W
A
C
K
L
C
R
S
P
E
G
F
G
P
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
98.4
92.7
N.A.
67.3
95.6
N.A.
N.A.
31.8
N.A.
76.2
N.A.
29.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98.9
94.6
N.A.
79.9
97.1
N.A.
N.A.
52
N.A.
85.1
N.A.
46.8
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
6.6
93.3
N.A.
N.A.
13.3
N.A.
66.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
13.3
100
N.A.
N.A.
26.6
N.A.
86.6
N.A.
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.4
29.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.9
52.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
10
0
46
46
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
10
46
0
0
0
0
% D
% Glu:
0
46
0
0
0
10
10
10
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
19
0
55
0
10
% G
% His:
0
0
10
28
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
10
0
0
0
0
10
10
10
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
10
0
19
10
10
10
0
19
10
0
0
19
0
46
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
19
10
46
10
0
0
10
0
10
0
0
10
0
0
19
% N
% Pro:
0
0
0
0
10
0
10
0
10
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
37
0
10
0
% Q
% Arg:
10
0
0
10
0
0
10
0
37
0
0
0
10
0
0
% R
% Ser:
37
0
0
10
64
0
0
10
0
0
10
0
0
0
0
% S
% Thr:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
10
0
46
0
19
0
46
0
% V
% Trp:
10
0
0
0
0
0
0
0
10
0
19
0
0
10
10
% W
% Tyr:
0
0
0
0
0
10
0
46
10
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _