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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNA1
All Species:
26.97
Human Site:
T448
Identified Species:
65.93
UniProt:
Q09470
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09470
NP_000208.2
495
56466
T448
L
S
R
R
S
S
S
T
M
S
K
S
E
Y
M
Chimpanzee
Pan troglodytes
XP_522328
495
56433
T448
L
S
R
R
S
S
S
T
M
S
K
S
E
Y
M
Rhesus Macaque
Macaca mulatta
XP_001102027
495
56463
T448
L
S
R
R
S
S
S
T
M
S
K
S
E
Y
M
Dog
Lupus familis
XP_543859
495
56374
T448
L
S
R
R
S
S
S
T
I
S
K
S
E
Y
M
Cat
Felis silvestris
Mouse
Mus musculus
P16388
495
56391
T448
L
S
R
R
S
S
S
T
I
S
K
S
E
Y
M
Rat
Rattus norvegicus
P10499
495
56361
T448
L
S
R
R
S
S
S
T
I
S
K
S
E
Y
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q7T199
516
58965
N464
P
V
P
V
I
V
S
N
F
N
Y
F
Y
H
R
Frog
Xenopus laevis
P22739
499
56683
A450
D
L
Q
K
S
R
S
A
S
T
L
S
K
S
D
Zebra Danio
Brachydanio rerio
XP_001334455
492
55803
T445
S
S
R
R
S
S
S
T
V
S
K
S
E
Y
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08510
655
74175
K518
T
L
G
Q
H
M
K
K
S
S
L
S
E
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.5
98.7
N.A.
98.3
98.1
N.A.
N.A.
61.2
77.5
86.2
N.A.
52.5
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
99.5
99.1
N.A.
98.9
98.7
N.A.
N.A.
75.1
86.3
92.7
N.A.
62.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
6.6
20
86.6
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
46.6
93.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
80
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
10
0
0
0
30
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
10
10
0
0
70
0
10
0
0
% K
% Leu:
60
20
0
0
0
0
0
0
0
0
20
0
0
0
0
% L
% Met:
0
0
0
0
0
10
0
0
30
0
0
0
0
0
70
% M
% Asn:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% N
% Pro:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
70
70
0
10
0
0
0
0
0
0
0
0
10
% R
% Ser:
10
70
0
0
80
70
90
0
20
80
0
90
0
20
10
% S
% Thr:
10
0
0
0
0
0
0
70
0
10
0
0
0
0
0
% T
% Val:
0
10
0
10
0
10
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
10
70
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _