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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL30
All Species:
20
Human Site:
Y398
Identified Species:
44
UniProt:
Q0D2K2
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0D2K2
NP_940984.2
578
64004
Y398
E
V
E
S
Y
D
P
Y
T
D
S
W
T
P
V
Chimpanzee
Pan troglodytes
XP_510571
589
65852
S408
G
V
F
P
A
S
P
S
V
S
L
K
Q
V
E
Rhesus Macaque
Macaca mulatta
XP_001086595
578
64164
Y398
E
V
E
S
Y
D
P
Y
T
D
S
W
T
P
I
Dog
Lupus familis
XP_848947
1076
118815
Y896
E
V
E
T
Y
D
P
Y
T
D
T
W
T
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3F7
581
64587
Y399
E
V
E
R
Y
D
P
Y
T
D
S
W
A
P
V
Rat
Rattus norvegicus
Q56A24
600
68346
Q383
D
V
W
I
Y
N
S
Q
L
N
I
W
I
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513676
594
65265
P401
A
K
T
A
P
H
L
P
Q
P
Y
A
G
L
Q
Chicken
Gallus gallus
XP_422662
591
65886
Y411
E
V
E
R
Y
D
P
Y
N
Q
S
W
A
A
I
Frog
Xenopus laevis
Q6INL2
589
66424
Y407
E
V
E
C
Y
D
P
Y
S
G
T
W
S
L
I
Zebra Danio
Brachydanio rerio
Q1LYM6
583
66823
A353
S
G
D
S
A
V
S
A
T
V
Y
T
L
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
K440
H
V
E
R
Y
D
P
K
E
N
K
W
S
K
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
29.8
97
48.6
N.A.
87
28.6
N.A.
50.1
64.8
59.5
27.2
N.A.
25.2
N.A.
N.A.
N.A.
Protein Similarity:
100
47.7
98.6
50.9
N.A.
92.4
46
N.A.
62.4
78.3
73
45.2
N.A.
42.2
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
93.3
80
N.A.
86.6
26.6
N.A.
0
60
53.3
13.3
N.A.
46.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
86.6
46.6
N.A.
6.6
66.6
80
26.6
N.A.
60
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
19
0
0
10
0
0
0
10
19
10
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
64
0
0
0
37
0
0
0
0
0
% D
% Glu:
55
0
64
0
0
0
0
0
10
0
0
0
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
28
% I
% Lys:
0
10
0
0
0
0
0
10
0
0
10
10
0
10
0
% K
% Leu:
0
0
0
0
0
0
10
0
10
0
10
0
10
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
10
19
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
0
73
10
0
10
0
0
0
37
0
% P
% Gln:
0
0
0
0
0
0
0
10
10
10
0
0
10
0
10
% Q
% Arg:
0
0
0
28
0
0
0
0
0
0
0
0
0
10
0
% R
% Ser:
10
0
0
28
0
10
19
10
10
10
37
0
19
10
0
% S
% Thr:
0
0
10
10
0
0
0
0
46
0
19
10
28
0
0
% T
% Val:
0
82
0
0
0
10
0
0
10
10
0
0
0
10
37
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
73
0
0
0
% W
% Tyr:
0
0
0
0
73
0
0
55
0
0
19
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _