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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIPPLY1
All Species:
21.82
Human Site:
S134
Identified Species:
60
UniProt:
Q0D2K3
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0D2K3
NP_612391.1
151
16379
S134
T
I
N
L
Y
E
D
S
D
S
E
E
E
E
E
Chimpanzee
Pan troglodytes
XP_001143526
151
16312
S134
T
I
N
L
Y
E
D
S
D
S
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001089822
151
16393
S134
T
I
N
L
Y
E
D
S
D
N
E
E
E
E
E
Dog
Lupus familis
XP_852844
187
20560
S134
T
I
N
L
Y
E
D
S
D
D
E
E
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q2WG77
201
21786
S137
T
I
N
L
Y
E
D
S
D
S
A
D
N
E
E
Rat
Rattus norvegicus
XP_001058466
207
21933
S159
T
I
N
L
Y
E
D
S
D
S
E
E
D
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_419859
131
14215
E122
E
E
D
E
G
E
L
E
Q
N
S
R
T
Q
S
Frog
Xenopus laevis
Q8QGU6
121
13920
D112
Q
E
T
D
S
D
S
D
S
E
E
E
D
I
Y
Zebra Danio
Brachydanio rerio
Q2WG80
140
16190
L130
E
S
D
V
E
D
C
L
K
H
N
S
H
F
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.6
95.3
51.3
N.A.
50.2
52.1
N.A.
N.A.
37
29.1
41
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.3
98
60.4
N.A.
52.7
57.9
N.A.
N.A.
50.9
43.7
56.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
80
93.3
N.A.
N.A.
6.6
13.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
100
N.A.
N.A.
26.6
26.6
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
23
12
0
23
67
12
67
12
0
12
23
0
0
% D
% Glu:
23
23
0
12
12
78
0
12
0
12
67
67
45
67
67
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
0
12
0
0
% H
% Ile:
0
67
0
0
0
0
0
0
0
0
0
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% K
% Leu:
0
0
0
67
0
0
12
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
67
0
0
0
0
0
0
23
12
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
12
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
0
12
0
0
12
0
12
67
12
45
12
12
0
0
12
% S
% Thr:
67
0
12
0
0
0
0
0
0
0
0
0
12
0
12
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _