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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBC1D8B All Species: 11.52
Human Site: S1044 Identified Species: 31.67
UniProt: Q0IIM8 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q0IIM8 NP_060222.2 1120 128709 S1044 T S S A K G F S G T V C G S G
Chimpanzee Pan troglodytes XP_521207 1118 128838 S1042 T S S A K G F S G T V C G S G
Rhesus Macaque Macaca mulatta XP_001106366 1112 127251 Q1040 A D T G K T P Q D S Q A F P E
Dog Lupus familis XP_549172 1130 129509 S1054 T A S A K E F S G T V C A S G
Cat Felis silvestris
Mouse Mus musculus A3KGB4 1114 127874 R1043 A S S A S T A R D S G P S E G
Rat Rattus norvegicus XP_001055741 1112 127329 Q1032 Q A S A P P E Q D S V F A E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513041 1244 141844 S1171 L S P A E D P S A E A G E R L
Chicken Gallus gallus XP_420352 1088 124138 A1007 T S P V R S P A A T T E V S A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio B0R0W9 1108 126719 T1034 N S T S H P S T P T S S P T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.7 53.5 88.7 N.A. 90.6 54.9 N.A. 73.8 76.1 N.A. 60.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.6 70 93.2 N.A. 94.8 71.6 N.A. 81.2 85.1 N.A. 74.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 80 N.A. 26.6 20 N.A. 20 26.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 86.6 N.A. 33.3 33.3 N.A. 26.6 40 N.A. 40 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 23 23 0 67 0 0 12 12 23 0 12 12 23 0 23 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 % C
% Asp: 0 12 0 0 0 12 0 0 34 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 12 12 12 0 0 12 0 12 12 23 23 % E
% Phe: 0 0 0 0 0 0 34 0 0 0 0 12 12 0 0 % F
% Gly: 0 0 0 12 0 23 0 0 34 0 12 12 23 0 45 % G
% His: 0 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 45 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 12 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 23 0 12 23 34 0 12 0 0 12 12 12 0 % P
% Gln: 12 0 0 0 0 0 0 23 0 0 12 0 0 0 0 % Q
% Arg: 0 0 0 0 12 0 0 12 0 0 0 0 0 12 0 % R
% Ser: 0 67 56 12 12 12 12 45 0 34 12 12 12 45 0 % S
% Thr: 45 0 23 0 0 23 0 12 0 56 12 0 0 12 0 % T
% Val: 0 0 0 12 0 0 0 0 0 0 45 0 12 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _