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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBC1D8B
All Species:
12.73
Human Site:
T735
Identified Species:
35
UniProt:
Q0IIM8
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0IIM8
NP_060222.2
1120
128709
T735
S
N
V
S
D
E
K
T
S
H
T
R
V
D
I
Chimpanzee
Pan troglodytes
XP_521207
1118
128838
T733
S
N
V
S
D
E
K
T
S
H
T
R
V
D
I
Rhesus Macaque
Macaca mulatta
XP_001106366
1112
127251
E735
A
F
F
S
D
D
Q
E
P
Y
P
V
T
D
I
Dog
Lupus familis
XP_549172
1130
129509
G745
S
N
V
S
G
E
K
G
N
Y
I
R
V
D
I
Cat
Felis silvestris
Mouse
Mus musculus
A3KGB4
1114
127874
S734
S
N
I
S
N
E
K
S
D
H
T
K
V
D
I
Rat
Rattus norvegicus
XP_001055741
1112
127329
E730
A
F
F
S
D
D
Q
E
P
C
P
V
T
D
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513041
1244
141844
S862
S
N
T
S
D
A
K
S
S
H
T
K
V
D
V
Chicken
Gallus gallus
XP_420352
1088
124138
G698
S
N
L
S
D
A
K
G
D
H
P
K
V
D
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
B0R0W9
1108
126719
K716
A
S
A
T
A
N
D
K
S
I
Q
K
V
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
53.5
88.7
N.A.
90.6
54.9
N.A.
73.8
76.1
N.A.
60.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
96.6
70
93.2
N.A.
94.8
71.6
N.A.
81.2
85.1
N.A.
74.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
66.6
N.A.
66.6
26.6
N.A.
66.6
60
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
53.3
80
N.A.
93.3
46.6
N.A.
86.6
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
12
0
12
23
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% C
% Asp:
0
0
0
0
67
23
12
0
23
0
0
0
0
100
0
% D
% Glu:
0
0
0
0
0
45
0
23
0
0
0
0
0
0
0
% E
% Phe:
0
23
23
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
12
0
0
23
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
56
0
0
0
0
0
% H
% Ile:
0
0
12
0
0
0
0
0
0
12
12
0
0
0
89
% I
% Lys:
0
0
0
0
0
0
67
12
0
0
0
45
0
0
0
% K
% Leu:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
67
0
0
12
12
0
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
23
0
34
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
23
0
0
0
12
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% R
% Ser:
67
12
0
89
0
0
0
23
45
0
0
0
0
0
0
% S
% Thr:
0
0
12
12
0
0
0
23
0
0
45
0
23
0
0
% T
% Val:
0
0
34
0
0
0
0
0
0
0
0
23
78
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
23
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _