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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FCHO2
All Species:
10.3
Human Site:
S422
Identified Species:
28.33
UniProt:
Q0JRZ9
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0JRZ9
NP_001139504.1
810
88924
S422
P
P
N
E
K
G
T
S
D
L
L
A
W
D
P
Chimpanzee
Pan troglodytes
XP_526898
810
88828
S422
P
P
N
E
K
G
T
S
D
L
L
A
W
D
P
Rhesus Macaque
Macaca mulatta
XP_001099245
809
88893
T421
A
P
P
N
E
K
G
T
S
D
L
L
A
W
D
Dog
Lupus familis
XP_535271
918
100423
D530
S
N
E
K
G
T
S
D
L
L
A
W
D
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UQN2
809
88716
T421
S
L
P
T
E
K
G
T
N
D
L
L
A
W
D
Rat
Rattus norvegicus
XP_219503
855
93612
T467
S
L
P
T
E
K
G
T
N
D
L
L
A
W
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512954
688
75120
S304
K
K
D
K
D
A
E
S
V
E
C
P
D
A
D
Chicken
Gallus gallus
XP_001232744
865
94579
D477
T
N
E
K
G
N
S
D
L
L
A
W
D
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q502I9
848
93639
S460
S
S
S
S
L
P
Q
S
S
V
P
P
P
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
85.1
N.A.
94.8
90
N.A.
73.5
79
N.A.
67
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.6
86.5
N.A.
97.9
92.7
N.A.
78.1
86.5
N.A.
80.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
6.6
N.A.
6.6
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
20
N.A.
26.6
26.6
N.A.
20
20
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
0
12
0
0
0
0
23
23
34
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% C
% Asp:
0
0
12
0
12
0
0
23
23
34
0
0
34
23
45
% D
% Glu:
0
0
23
23
34
0
12
0
0
12
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
23
23
34
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
34
23
34
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
23
0
0
12
0
0
0
23
45
56
34
0
0
23
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
23
23
12
0
12
0
0
23
0
0
0
0
12
0
% N
% Pro:
23
34
34
0
0
12
0
0
0
0
12
23
12
23
23
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
45
12
12
12
0
0
23
45
23
0
0
0
0
0
0
% S
% Thr:
12
0
0
23
0
12
23
34
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
23
23
34
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _