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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCXD2
All Species:
19.39
Human Site:
S259
Identified Species:
42.67
UniProt:
Q0VAA5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0VAA5
NP_695000.1
305
34777
S259
S
E
R
A
S
R
G
S
F
H
V
S
Q
A
I
Chimpanzee
Pan troglodytes
XP_001146704
329
37141
S247
S
E
R
A
S
R
G
S
F
H
V
S
Q
A
I
Rhesus Macaque
Macaca mulatta
XP_001097679
329
37108
S247
S
E
R
A
P
R
G
S
F
H
V
S
Q
A
I
Dog
Lupus familis
XP_849099
329
37112
S247
S
E
R
A
P
R
G
S
F
H
V
S
Q
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLJ3
321
36295
S241
T
E
R
R
K
K
G
S
F
F
I
S
Q
V
V
Rat
Rattus norvegicus
NP_001127953
340
38639
A259
S
E
R
A
P
R
G
A
F
H
V
S
Q
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505659
240
27310
I195
T
T
D
P
E
K
L
I
Q
F
L
Q
A
S
I
Chicken
Gallus gallus
XP_416631
315
36185
L259
V
R
G
L
K
N
T
L
V
H
R
N
L
P
M
Frog
Xenopus laevis
NP_001079447
307
35506
L256
L
P
R
L
K
S
G
L
K
N
T
L
V
R
R
Zebra Danio
Brachydanio rerio
Q58EK3
322
36584
T241
K
D
R
R
R
K
G
T
F
F
V
S
Q
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120325
297
34613
L250
C
G
T
L
Q
R
D
L
V
P
L
C
Q
K
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
85.7
82.3
N.A.
45.7
83.2
N.A.
42.6
67.3
60.9
45.9
N.A.
N.A.
31.4
N.A.
N.A.
Protein Similarity:
100
86.9
86.6
84.8
N.A.
65.7
86.1
N.A.
58.3
76.5
70
63.6
N.A.
N.A.
49.1
N.A.
N.A.
P-Site Identity:
100
100
93.3
93.3
N.A.
46.6
86.6
N.A.
6.6
6.6
13.3
40
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
100
100
93.3
93.3
N.A.
73.3
93.3
N.A.
33.3
20
20
66.6
N.A.
N.A.
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
46
0
0
0
10
0
0
0
0
10
46
10
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
10
10
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
55
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
64
28
0
0
0
0
0
% F
% Gly:
0
10
10
0
0
0
73
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
55
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
55
% I
% Lys:
10
0
0
0
28
28
0
0
10
0
0
0
0
10
0
% K
% Leu:
10
0
0
28
0
0
10
28
0
0
19
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
10
0
10
28
0
0
0
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
0
10
0
0
0
10
0
0
10
73
0
0
% Q
% Arg:
0
10
73
19
10
55
0
0
0
0
10
0
0
10
10
% R
% Ser:
46
0
0
0
19
10
0
46
0
0
0
64
0
10
0
% S
% Thr:
19
10
10
0
0
0
10
10
0
0
10
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
0
19
0
55
0
10
19
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _