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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1B
All Species:
14.24
Human Site:
S244
Identified Species:
39.17
UniProt:
Q0VAM2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0VAM2
NP_689758.1
473
55359
S244
D
P
L
D
N
D
K
S
C
Y
S
E
R
K
K
Chimpanzee
Pan troglodytes
XP_001153731
467
53007
T238
N
K
D
P
L
A
S
T
K
P
C
F
S
D
K
Rhesus Macaque
Macaca mulatta
XP_001084596
560
64388
S283
G
P
L
D
N
D
K
S
C
Y
S
E
R
K
K
Dog
Lupus familis
XP_848924
466
54546
S244
D
P
L
D
N
D
K
S
C
Y
S
E
R
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZL7
473
55255
S244
D
P
L
D
N
D
K
S
C
Y
S
E
R
K
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
K293
M
D
S
L
D
N
H
K
C
R
G
D
V
T
K
Chicken
Gallus gallus
XP_414615
480
55173
K251
K
D
P
L
D
G
T
K
P
C
F
S
D
Q
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
N285
D
P
L
D
N
D
K
N
C
F
S
D
H
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
V375
N
D
G
D
G
Q
T
V
K
F
Q
D
L
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
76
97
N.A.
97.4
N.A.
N.A.
56.3
70
N.A.
78.7
N.A.
N.A.
N.A.
N.A.
47.1
Protein Similarity:
100
77.3
77.6
98.3
N.A.
99.3
N.A.
N.A.
72.4
82.7
N.A.
86.3
N.A.
N.A.
N.A.
N.A.
62
P-Site Identity:
100
6.6
93.3
100
N.A.
100
N.A.
N.A.
13.3
6.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
20
93.3
100
N.A.
100
N.A.
N.A.
33.3
20
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
67
12
12
0
0
0
0
% C
% Asp:
45
34
12
67
23
56
0
0
0
0
0
34
12
12
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
45
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
23
12
12
0
0
0
% F
% Gly:
12
0
12
0
12
12
0
0
0
0
12
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
12
0
0
0
0
56
23
23
0
0
0
0
67
89
% K
% Leu:
0
0
56
23
12
0
0
0
0
0
0
0
12
0
0
% L
% Met:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
0
0
56
12
0
12
0
0
0
0
0
0
0
% N
% Pro:
0
56
12
12
0
0
0
0
12
12
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
12
0
0
0
0
12
0
0
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
12
0
0
45
0
12
% R
% Ser:
0
0
12
0
0
0
12
45
0
0
56
12
12
0
0
% S
% Thr:
0
0
0
0
0
0
23
12
0
0
0
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
45
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _