KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1B
All Species:
16.67
Human Site:
Y149
Identified Species:
45.83
UniProt:
Q0VAM2
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0VAM2
NP_689758.1
473
55359
Y149
A
S
G
E
E
Q
T
Y
R
K
N
V
Q
Q
M
Chimpanzee
Pan troglodytes
XP_001153731
467
53007
Y149
A
P
C
D
E
Q
A
Y
R
K
R
M
H
Q
L
Rhesus Macaque
Macaca mulatta
XP_001084596
560
64388
Y188
A
S
G
E
E
Q
T
Y
R
K
N
V
Q
Q
M
Dog
Lupus familis
XP_848924
466
54546
Y149
A
S
G
E
E
Q
T
Y
R
K
N
V
Q
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZL7
473
55255
Y149
A
S
G
E
E
Q
T
Y
R
K
N
V
Q
Q
M
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
G197
T
Q
C
D
E
E
N
G
T
V
K
K
I
I
S
Chicken
Gallus gallus
XP_414615
480
55173
W158
A
P
C
D
E
A
Y
W
K
K
M
N
Q
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
R191
S
T
G
E
D
L
Y
R
K
A
V
Q
Q
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
L280
C
I
A
I
D
P
T
L
R
K
S
A
G
Q
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.4
76
97
N.A.
97.4
N.A.
N.A.
56.3
70
N.A.
78.7
N.A.
N.A.
N.A.
N.A.
47.1
Protein Similarity:
100
77.3
77.6
98.3
N.A.
99.3
N.A.
N.A.
72.4
82.7
N.A.
86.3
N.A.
N.A.
N.A.
N.A.
62
P-Site Identity:
100
46.6
100
100
N.A.
100
N.A.
N.A.
6.6
26.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
66.6
100
100
N.A.
100
N.A.
N.A.
20
53.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
0
12
0
0
12
12
0
0
12
0
12
0
0
0
% A
% Cys:
12
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
23
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
56
78
12
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
56
0
0
0
0
12
0
0
0
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
12
0
12
0
0
0
0
0
0
0
0
12
12
0
% I
% Lys:
0
0
0
0
0
0
0
0
23
78
12
12
0
0
0
% K
% Leu:
0
0
0
0
0
12
0
12
0
0
0
0
0
12
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
12
12
0
12
45
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
45
12
0
0
0
% N
% Pro:
0
23
0
0
0
12
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
0
0
56
0
0
0
0
0
12
67
67
0
% Q
% Arg:
0
0
0
0
0
0
0
12
67
0
12
0
0
0
0
% R
% Ser:
12
45
0
0
0
0
0
0
0
0
12
0
0
0
12
% S
% Thr:
12
12
0
0
0
0
56
0
12
0
0
0
0
0
12
% T
% Val:
0
0
0
0
0
0
0
0
0
12
12
45
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
23
56
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _