KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPA14
All Species:
25.76
Human Site:
S246
Identified Species:
40.48
UniProt:
Q0VDF9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q0VDF9
NP_057383.2
509
54794
S246
L
A
S
E
F
Q
R
S
F
K
H
D
V
R
G
Chimpanzee
Pan troglodytes
XP_507667
509
54749
S246
L
A
S
E
F
Q
R
S
F
K
H
D
V
R
G
Rhesus Macaque
Macaca mulatta
XP_001088421
509
54863
S246
L
A
S
E
F
Q
R
S
F
K
H
D
V
K
G
Dog
Lupus familis
XP_535180
509
54970
A246
L
A
S
E
F
Q
R
A
F
K
H
D
V
R
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99M31
509
54632
L246
L
A
S
E
F
Q
R
L
F
K
H
D
V
R
G
Rat
Rattus norvegicus
Q6AYB4
509
54445
L246
L
A
S
E
F
Q
R
L
F
K
H
D
V
R
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515568
521
56614
S257
L
A
S
E
F
Q
R
S
F
K
H
D
V
R
E
Chicken
Gallus gallus
XP_416996
895
96028
S242
L
A
S
E
F
Q
R
S
C
K
H
D
I
R
G
Frog
Xenopus laevis
NP_001092168
509
54429
T246
L
A
S
E
F
Q
R
T
Y
K
Q
D
I
R
G
Zebra Danio
Brachydanio rerio
NP_001038541
504
54251
T246
L
A
A
E
F
K
K
T
F
K
Q
D
V
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02825
642
70141
K246
L
A
D
E
F
K
R
K
Y
K
K
D
L
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P09446
640
69704
K249
F
C
A
E
F
K
R
K
H
K
K
D
L
A
S
Sea Urchin
Strong. purpuratus
XP_792940
488
52873
Q243
C
A
I
E
F
K
R
Q
S
R
M
D
I
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09435
649
70528
K246
L
A
T
E
F
K
R
K
T
K
K
D
I
S
N
Red Bread Mold
Neurospora crassa
Q01233
646
70535
K246
F
V
Q
E
F
K
R
K
H
K
K
D
L
S
T
Conservation
Percent
Protein Identity:
100
99
98.2
95
N.A.
90.9
90.3
N.A.
82.3
47.3
75.4
70.3
N.A.
32.4
N.A.
30.9
38.1
Protein Similarity:
100
100
99.2
98.2
N.A.
96.2
96.6
N.A.
89
53.2
88
83.6
N.A.
49.5
N.A.
47.8
55.9
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
86.6
73.3
60
N.A.
53.3
N.A.
33.3
33.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
86.6
N.A.
73.3
N.A.
53.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.8
31.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.3
48.3
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
33.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
66.6
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
87
14
0
0
0
0
7
0
0
0
0
0
7
0
% A
% Cys:
7
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
100
0
0
7
% D
% Glu:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
14
0
0
0
100
0
0
0
54
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% G
% His:
0
0
0
0
0
0
0
0
14
0
54
0
0
0
0
% H
% Ile:
0
0
7
0
0
0
0
0
0
0
0
0
27
0
0
% I
% Lys:
0
0
0
0
0
40
7
27
0
94
27
0
0
7
0
% K
% Leu:
80
0
0
0
0
0
0
14
0
0
0
0
20
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
7
0
0
60
0
7
0
0
14
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
94
0
0
7
0
0
0
60
0
% R
% Ser:
0
0
60
0
0
0
0
34
7
0
0
0
0
20
14
% S
% Thr:
0
0
7
0
0
0
0
14
7
0
0
0
0
7
7
% T
% Val:
0
7
0
0
0
0
0
0
0
0
0
0
54
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
14
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _