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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEXN All Species: 22.73
Human Site: S313 Identified Species: 50
UniProt: Q0ZGT2 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q0ZGT2 NP_653174.3 675 80658 S313 R P G K L K L S F E E M E R Q
Chimpanzee Pan troglodytes XP_001169260 676 80785 S313 R P G K L K L S F E E M E R Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_547323 987 112332 S624 R P G K L K L S F E E I E R Q
Cat Felis silvestris
Mouse Mus musculus Q7TPW1 607 72119 A273 R R L E E E K A A F A E A R R
Rat Rattus norvegicus Q9Z2J4 656 78375 S293 R P G K L R L S F E E I E R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506582 429 50761 L191 E Y E E L I K L K R S G S I Q
Chicken Gallus gallus
Frog Xenopus laevis O42287 1270 143652 I547 I P E K Q S L I D Q L K Q V Q
Zebra Danio Brachydanio rerio NP_001077324 861 101692 S416 R P G K L R L S F E E L E R Q
Tiger Blowfish Takifugu rubipres NP_001171363 815 96132 S386 R P G K L R L S F E E L E R Q
Fruit Fly Dros. melanogaster Q9VL63 290 35507 H52 E V N N H G R H R E R D R D R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41954 1006 118043 R449 Q L L E D Q C R A K Q E K E K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 N.A. 65.1 N.A. 79.4 84 N.A. 52.5 N.A. 20 51 54.3 21.7 N.A. 20.1 N.A.
Protein Similarity: 100 99.2 N.A. 67.3 N.A. 85.1 92.7 N.A. 59.2 N.A. 32.7 65.7 69.3 32.4 N.A. 36.1 N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 13.3 86.6 N.A. 13.3 N.A. 26.6 86.6 86.6 6.6 N.A. 0 N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 40 100 N.A. 20 N.A. 40 100 100 13.3 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 19 0 10 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 10 0 0 10 0 10 0 % D
% Glu: 19 0 19 28 10 10 0 0 0 64 55 19 55 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 55 10 0 0 0 0 0 % F
% Gly: 0 0 55 0 0 10 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 10 0 10 0 0 0 19 0 10 0 % I
% Lys: 0 0 0 64 0 28 19 0 10 10 0 10 10 0 10 % K
% Leu: 0 10 19 0 64 0 64 10 0 0 10 19 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 19 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 64 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 10 10 0 0 0 10 10 0 10 0 73 % Q
% Arg: 64 10 0 0 0 28 10 10 10 10 10 0 10 64 19 % R
% Ser: 0 0 0 0 0 10 0 55 0 0 10 0 10 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _