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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1B1
All Species:
23.64
Human Site:
S602
Identified Species:
65
UniProt:
Q10567
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10567
NP_001118.2
949
104637
S602
P
R
T
A
S
S
E
S
A
E
S
P
E
T
A
Chimpanzee
Pan troglodytes
XP_001174130
948
105725
A602
I
H
H
G
S
T
D
A
G
D
S
P
V
G
T
Rhesus Macaque
Macaca mulatta
XP_001105882
949
104563
S602
P
R
T
A
S
S
E
S
A
E
S
P
E
T
A
Dog
Lupus familis
XP_852198
949
104720
S602
P
R
T
A
S
N
E
S
T
E
S
P
E
T
A
Cat
Felis silvestris
Mouse
Mus musculus
O35643
943
103960
S602
P
R
T
A
S
S
E
S
T
E
S
P
E
T
A
Rat
Rattus norvegicus
P52303
949
104570
S602
P
R
T
A
S
S
E
S
T
E
S
P
E
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090605
946
103868
S602
P
R
T
G
S
N
E
S
A
E
S
P
E
A
A
Zebra Danio
Brachydanio rerio
NP_001122002
947
104229
S602
A
R
A
G
S
G
E
S
A
E
S
P
E
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
D425
R
Q
D
T
I
K
D
D
C
C
I
S
L
C
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
99.1
98.4
N.A.
95.6
96
N.A.
N.A.
N.A.
88.5
87.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.3
99.3
98.8
N.A.
96.6
96.8
N.A.
N.A.
N.A.
93
91.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
100
86.6
N.A.
93.3
86.6
N.A.
N.A.
N.A.
80
60
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
93.3
N.A.
93.3
86.6
N.A.
N.A.
N.A.
86.6
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
56
0
0
0
12
45
0
0
0
0
23
67
% A
% Cys:
0
0
0
0
0
0
0
0
12
12
0
0
0
12
0
% C
% Asp:
0
0
12
0
0
0
23
12
0
12
0
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
78
0
0
78
0
0
78
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
34
0
12
0
0
12
0
0
0
0
12
12
% G
% His:
0
12
12
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
0
0
12
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
23
0
0
0
0
0
0
0
0
0
% N
% Pro:
67
0
0
0
0
0
0
0
0
0
0
89
0
0
0
% P
% Gln:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
12
78
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
89
45
0
78
0
0
89
12
0
0
0
% S
% Thr:
0
0
67
12
0
12
0
0
34
0
0
0
0
45
12
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _