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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP1B1
All Species:
16.67
Human Site:
S875
Identified Species:
45.83
UniProt:
Q10567
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10567
NP_001118.2
949
104637
S875
L
N
A
E
A
A
S
S
K
L
Q
S
S
N
I
Chimpanzee
Pan troglodytes
XP_001174130
948
105725
S874
L
N
A
D
T
V
S
S
K
L
Q
N
N
N
V
Rhesus Macaque
Macaca mulatta
XP_001105882
949
104563
S875
L
N
A
E
A
V
S
S
K
L
Q
S
S
N
I
Dog
Lupus familis
XP_852198
949
104720
S875
L
N
A
E
A
V
S
S
R
L
Q
S
S
N
I
Cat
Felis silvestris
Mouse
Mus musculus
O35643
943
103960
N872
L
N
T
E
A
A
S
N
K
L
Q
S
S
N
I
Rat
Rattus norvegicus
P52303
949
104570
S878
L
N
T
E
A
A
S
S
K
L
Q
S
S
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090605
946
103868
N875
S
S
S
D
A
V
I
N
K
L
Q
A
S
N
I
Zebra Danio
Brachydanio rerio
NP_001122002
947
104229
N876
L
N
S
D
A
A
S
N
K
L
Q
G
S
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P36000
726
81850
L655
T
N
T
N
A
G
M
L
N
T
L
T
T
L
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.8
99.1
98.4
N.A.
95.6
96
N.A.
N.A.
N.A.
88.5
87.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.3
99.3
98.8
N.A.
96.6
96.8
N.A.
N.A.
N.A.
93
91.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
93.3
86.6
N.A.
86.6
93.3
N.A.
N.A.
N.A.
46.6
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
N.A.
80
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
45
0
89
45
0
0
0
0
0
12
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
56
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
78
% I
% Lys:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% K
% Leu:
78
0
0
0
0
0
0
12
0
89
12
0
0
12
0
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
0
89
0
12
0
0
0
34
12
0
0
12
12
89
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
89
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% R
% Ser:
12
12
23
0
0
0
78
56
0
0
0
56
78
0
0
% S
% Thr:
12
0
34
0
12
0
0
0
0
12
0
12
12
0
0
% T
% Val:
0
0
0
0
0
45
0
0
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _