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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AP1B1 All Species: 31.82
Human Site: T164 Identified Species: 87.5
UniProt: Q10567 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q10567 NP_001118.2 949 104637 T164 E D Q G F L D T L K D L I S D
Chimpanzee Pan troglodytes XP_001174130 948 105725 S164 E D Q G F L D S L R D L I A D
Rhesus Macaque Macaca mulatta XP_001105882 949 104563 T164 E D Q G F L D T L K D L I S D
Dog Lupus familis XP_852198 949 104720 T164 E D Q G F L D T L K D L I S D
Cat Felis silvestris
Mouse Mus musculus O35643 943 103960 T164 E D Q G F L D T L K D L I S D
Rat Rattus norvegicus P52303 949 104570 T164 E D Q G F L D T L K D L I S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001090605 946 103868 T164 E D Q G F L D T L K D L I S D
Zebra Danio Brachydanio rerio NP_001122002 947 104229 T164 E D Q G F L D T L K D L I S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36000 726 81850 D14 R I K K F L K D S I R I A P K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 83.8 99.1 98.4 N.A. 95.6 96 N.A. N.A. N.A. 88.5 87.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 92.3 99.3 98.8 N.A. 96.6 96.8 N.A. N.A. N.A. 93 91.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 80 100 100 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 12 12 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 89 0 0 0 0 89 12 0 0 89 0 0 0 89 % D
% Glu: 89 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 89 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 12 0 0 0 0 0 0 0 12 0 12 89 0 0 % I
% Lys: 0 0 12 12 0 0 12 0 0 78 0 0 0 0 12 % K
% Leu: 0 0 0 0 0 100 0 0 89 0 0 89 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % P
% Gln: 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 12 0 0 0 0 0 0 0 0 12 12 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 12 12 0 0 0 0 78 0 % S
% Thr: 0 0 0 0 0 0 0 78 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _