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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CPSF1
All Species:
11.82
Human Site:
S1324
Identified Species:
21.67
UniProt:
Q10570
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10570
NP_037423.2
1443
160884
S1324
R
G
A
T
E
G
L
S
K
K
S
V
V
W
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532356
1499
165986
S1380
R
G
A
A
E
G
P
S
K
K
S
V
V
W
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EPU4
1441
160800
S1322
R
G
A
A
E
G
P
S
K
K
S
V
V
W
E
Rat
Rattus norvegicus
NP_001124043
1386
154862
S1267
R
G
A
A
E
G
P
S
K
K
S
V
M
W
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514888
831
91833
F722
Q
I
I
S
V
K
N
F
I
L
A
A
D
V
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001108153
1449
162918
N1330
R
G
T
L
D
T
A
N
K
K
A
L
T
W
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V726
1455
164663
Q1336
C
H
Q
K
G
L
H
Q
R
Q
P
F
L
Y
E
Honey Bee
Apis mellifera
XP_624382
1415
160872
K1296
I
S
D
P
A
N
D
K
K
H
F
S
D
A
D
Nematode Worm
Caenorhab. elegans
Q9N4C2
1454
162698
E1334
S
L
L
Q
L
N
N
E
D
E
K
E
A
I
E
Sea Urchin
Strong. purpuratus
XP_789715
1220
135970
Q1111
S
G
P
V
L
R
R
Q
V
V
F
F
A
T
L
Poplar Tree
Populus trichocarpa
XP_002318462
1455
159431
A1336
P
S
L
D
R
S
G
A
A
P
V
S
D
K
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGR0
1442
158057
I1330
V
S
S
G
A
D
K
I
N
R
F
A
L
L
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SEY2
1456
158155
L1318
V
Y
P
N
P
S
S
L
S
S
N
S
E
E
N
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.8
N.A.
96.5
92.8
N.A.
50.6
N.A.
N.A.
79.6
N.A.
46.7
54.3
31.5
47.6
Protein Similarity:
100
N.A.
N.A.
92.5
N.A.
98
94.3
N.A.
53.3
N.A.
N.A.
89.2
N.A.
65.5
71
52.2
60.7
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
86.6
80
N.A.
0
N.A.
N.A.
33.3
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
86.6
86.6
N.A.
20
N.A.
N.A.
66.6
N.A.
33.3
13.3
13.3
6.6
Percent
Protein Identity:
33.1
N.A.
N.A.
32.8
N.A.
28
Protein Similarity:
51.6
N.A.
N.A.
51.8
N.A.
48.7
P-Site Identity:
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
6.6
N.A.
N.A.
20
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
31
24
16
0
8
8
8
0
16
16
16
8
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
8
8
8
0
8
0
0
0
24
0
16
% D
% Glu:
0
0
0
0
31
0
0
8
0
8
0
8
8
8
47
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
24
16
0
0
8
% F
% Gly:
0
47
0
8
8
31
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
8
8
0
0
0
0
8
0
% I
% Lys:
0
0
0
8
0
8
8
8
47
39
8
0
0
8
0
% K
% Leu:
0
8
16
8
16
8
8
8
0
8
0
8
16
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
8
0
16
16
8
8
0
8
0
0
0
8
% N
% Pro:
8
0
16
8
8
0
24
0
0
8
8
0
0
0
0
% P
% Gln:
8
0
8
8
0
0
0
16
0
8
0
0
0
0
0
% Q
% Arg:
39
0
0
0
8
8
8
0
8
8
0
0
0
0
0
% R
% Ser:
16
24
8
8
0
16
8
31
8
8
31
24
0
0
0
% S
% Thr:
0
0
8
8
0
8
0
0
0
0
0
0
8
8
8
% T
% Val:
16
0
0
8
8
0
0
0
8
8
8
31
24
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
39
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _