Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF1 All Species: 32.42
Human Site: Y1407 Identified Species: 59.44
UniProt: Q10570 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q10570 NP_037423.2 1443 160884 Y1407 D G E L L N R Y L Y L S T M E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532356 1499 165986 Y1463 D G E L L N R Y L Y L S T M E
Cat Felis silvestris
Mouse Mus musculus Q9EPU4 1441 160800 Y1405 D G E L L N R Y L Y L S T M E
Rat Rattus norvegicus NP_001124043 1386 154862 Y1350 D G E L L N R Y L Y L S T M E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514888 831 91833 R796 K E S F G G M R L L R R A D F
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108153 1449 162918 Y1413 D G E L L N K Y L Y L S T M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V726 1455 164663 Y1419 D G D L I W S Y R L M A N S E
Honey Bee Apis mellifera XP_624382 1415 160872 Y1379 D G D L V W R Y L Y L P N N E
Nematode Worm Caenorhab. elegans Q9N4C2 1454 162698 Y1418 D G D V V E Q Y L H L S L Y D
Sea Urchin Strong. purpuratus XP_789715 1220 135970 C1185 G D L L L K Y C H L S V V E R
Poplar Tree Populus trichocarpa XP_002318462 1455 159431 Y1419 D C E M L S Y Y E M I P L E E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FGR0 1442 158057 Y1406 D C E L L C H Y E M L P L E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SEY2 1456 158155 F1408 D G K I L E R F L E L G T G K
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.8 N.A. 96.5 92.8 N.A. 50.6 N.A. N.A. 79.6 N.A. 46.7 54.3 31.5 47.6
Protein Similarity: 100 N.A. N.A. 92.5 N.A. 98 94.3 N.A. 53.3 N.A. N.A. 89.2 N.A. 65.5 71 52.2 60.7
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 N.A. N.A. 93.3 N.A. 33.3 60 40 13.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 6.6 N.A. N.A. 100 N.A. 60 73.3 80 13.3
Percent
Protein Identity: 33.1 N.A. N.A. 32.8 N.A. 28
Protein Similarity: 51.6 N.A. N.A. 51.8 N.A. 48.7
P-Site Identity: 33.3 N.A. N.A. 46.6 N.A. 46.6
P-Site Similarity: 53.3 N.A. N.A. 46.6 N.A. 73.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % A
% Cys: 0 16 0 0 0 8 0 8 0 0 0 0 0 0 0 % C
% Asp: 85 8 24 0 0 0 0 0 0 0 0 0 0 8 8 % D
% Glu: 0 8 54 0 0 16 0 0 16 8 0 0 0 24 70 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 8 % F
% Gly: 8 70 0 0 8 8 0 0 0 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 8 0 8 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 8 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 0 8 0 0 8 8 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 8 70 70 0 0 0 70 24 70 0 24 0 0 % L
% Met: 0 0 0 8 0 0 8 0 0 16 8 0 0 39 0 % M
% Asn: 0 0 0 0 0 39 0 0 0 0 0 0 16 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 24 0 0 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 47 8 8 0 8 8 0 0 8 % R
% Ser: 0 0 8 0 0 8 8 0 0 0 8 47 0 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 47 0 0 % T
% Val: 0 0 0 8 16 0 0 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 16 77 0 47 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _