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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPSF1 All Species: 33.94
Human Site: Y155 Identified Species: 62.22
UniProt: Q10570 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q10570 NP_037423.2 1443 160884 Y155 R C A A M L V Y G T R L V V L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_532356 1499 165986 Y213 R C A A M L I Y G T R L V V L
Cat Felis silvestris
Mouse Mus musculus Q9EPU4 1441 160800 Y155 R C A A M L I Y G T R L V V L
Rat Rattus norvegicus NP_001124043 1386 154862 Y155 R C A A M L I Y G T R L V V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514888 831 91833
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108153 1449 162918 Y155 R C A V M L V Y G T C L V V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V726 1455 164663 Y157 R C A V M L V Y G K R L V V L
Honey Bee Apis mellifera XP_624382 1415 160872 Y154 R C A V M L I Y G R K L V V L
Nematode Worm Caenorhab. elegans Q9N4C2 1454 162698 L154 S N R C A A C L V Y G K H I A
Sea Urchin Strong. purpuratus XP_789715 1220 135970 I36 A Q K V H P I I W S Q S S L P
Poplar Tree Populus trichocarpa XP_002318462 1455 159431 Y197 R C G G V L V Y D L Q M I I L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FGR0 1442 158057 Y200 R C G G V L V Y G L Q M I I L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7SEY2 1456 158155 Y164 E T V S I H Y Y E K E E L V G
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.8 N.A. 96.5 92.8 N.A. 50.6 N.A. N.A. 79.6 N.A. 46.7 54.3 31.5 47.6
Protein Similarity: 100 N.A. N.A. 92.5 N.A. 98 94.3 N.A. 53.3 N.A. N.A. 89.2 N.A. 65.5 71 52.2 60.7
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. 0 N.A. N.A. 86.6 N.A. 86.6 73.3 0 0
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 0 N.A. N.A. 86.6 N.A. 86.6 86.6 6.6 26.6
Percent
Protein Identity: 33.1 N.A. N.A. 32.8 N.A. 28
Protein Similarity: 51.6 N.A. N.A. 51.8 N.A. 48.7
P-Site Identity: 40 N.A. N.A. 46.6 N.A. 13.3
P-Site Similarity: 73.3 N.A. N.A. 80 N.A. 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 54 31 8 8 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 70 0 8 0 0 8 0 0 0 8 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 0 0 8 0 8 8 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 16 16 0 0 0 0 62 0 8 0 0 0 8 % G
% His: 0 0 0 0 8 8 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 8 0 39 8 0 0 0 0 16 24 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 16 8 8 0 0 0 % K
% Leu: 0 0 0 0 0 70 0 8 0 16 0 54 8 8 70 % L
% Met: 0 0 0 0 54 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 24 0 0 0 0 % Q
% Arg: 70 0 8 0 0 0 0 0 0 8 39 0 0 0 0 % R
% Ser: 8 0 0 8 0 0 0 0 0 8 0 8 8 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 39 0 0 0 0 0 % T
% Val: 0 0 8 31 16 0 39 0 8 0 0 0 54 62 0 % V
% Trp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 77 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _