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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PMPCA All Species: 15.76
Human Site: T58 Identified Species: 26.67
UniProt: Q10713 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q10713 NP_055975.1 525 58253 T58 V P K P V F A T V D G Q E K F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537796 526 58551 T59 V P E P V F A T V D G Q E K F
Cat Felis silvestris
Mouse Mus musculus Q9DC61 524 58261 T57 V P K P I F A T V D G Q E K F
Rat Rattus norvegicus P20069 524 58589 T57 V P K P I F A T V D G Q E K F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521013 513 57132 T59 K F E T K V T T L E N G L R V
Chicken Gallus gallus NP_001006197 519 57529 F59 A A E G R E R F E T R V T V L
Frog Xenopus laevis NP_001089466 518 57691 K57 A K V D G Q E K F E T K V T T
Zebra Danio Brachydanio rerio NP_001007443 517 57513 Y57 S V D G H E K Y E T K I T T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610333 556 61032 A85 N L P E A V Y A A P L A E S A
Honey Bee Apis mellifera XP_624556 358 40406
Nematode Worm Caenorhab. elegans P98080 471 51717 S27 R N A S S A V S V K D V L A S
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZU25 503 54383 M58 A A L T S L D M P L Q G V S L
Baker's Yeast Sacchar. cerevisiae P11914 482 53319 H38 A T S N T P G H F S A L G L Y
Red Bread Mold Neurospora crassa P11913 476 52538 P32 F R R G L A T P H S G T G I K
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.1 N.A. 91.2 86 N.A. 81.7 82 81.3 78.4 N.A. 47.8 32.1 25.5 N.A.
Protein Similarity: 100 N.A. N.A. 95.2 N.A. 95 90.4 N.A. 90.4 89.9 90.2 88 N.A. 66.3 46.6 44.5 N.A.
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 93.3 93.3 N.A. 6.6 0 0 0 N.A. 6.6 0 6.6 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 33.3 6.6 13.3 0 N.A. 6.6 0 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.6 34.4 29.5
Protein Similarity: N.A. N.A. N.A. 48 54.4 49.1
P-Site Identity: N.A. N.A. N.A. 0 0 6.6
P-Site Similarity: N.A. N.A. N.A. 0 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 15 8 0 8 15 29 8 8 0 8 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 0 0 8 0 0 29 8 0 0 0 0 % D
% Glu: 0 0 22 8 0 15 8 0 15 15 0 0 36 0 0 % E
% Phe: 8 8 0 0 0 29 0 8 15 0 0 0 0 0 29 % F
% Gly: 0 0 0 22 8 0 8 0 0 0 36 15 15 0 0 % G
% His: 0 0 0 0 8 0 0 8 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 15 0 0 0 0 0 0 8 0 8 0 % I
% Lys: 8 8 22 0 8 0 8 8 0 8 8 8 0 29 8 % K
% Leu: 0 8 8 0 8 8 0 0 8 8 8 8 15 8 22 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 8 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 29 8 29 0 8 0 8 8 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 8 0 0 0 0 8 29 0 0 0 % Q
% Arg: 8 8 8 0 8 0 8 0 0 0 8 0 0 8 0 % R
% Ser: 8 0 8 8 15 0 0 8 0 15 0 0 0 15 8 % S
% Thr: 0 8 0 15 8 0 15 36 0 15 8 8 15 15 8 % T
% Val: 29 8 8 0 15 15 8 0 36 0 0 15 15 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 8 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _