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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCA
All Species:
17.27
Human Site:
T67
Identified Species:
29.23
UniProt:
Q10713
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10713
NP_055975.1
525
58253
T67
D
G
Q
E
K
F
E
T
K
V
T
T
L
D
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537796
526
58551
T68
D
G
Q
E
K
F
E
T
K
V
T
T
L
D
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC61
524
58261
T66
D
G
Q
E
K
F
E
T
K
V
T
T
L
D
N
Rat
Rattus norvegicus
P20069
524
58589
T66
D
G
Q
E
K
F
E
T
K
V
T
T
L
D
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521013
513
57132
S68
E
N
G
L
R
V
A
S
Q
N
K
F
G
Q
F
Chicken
Gallus gallus
NP_001006197
519
57529
N68
T
R
V
T
V
L
E
N
G
L
R
V
A
S
Q
Frog
Xenopus laevis
NP_001089466
518
57691
E66
E
T
K
V
T
T
L
E
N
G
L
R
V
A
S
Zebra Danio
Brachydanio rerio
NP_001007443
517
57513
N66
T
K
I
T
T
L
E
N
G
L
K
I
A
S
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610333
556
61032
T94
P
L
A
E
S
A
I
T
K
V
T
T
L
P
N
Honey Bee
Apis mellifera
XP_624556
358
40406
Nematode Worm
Caenorhab. elegans
P98080
471
51717
P36
K
D
V
L
A
S
A
P
Q
A
E
V
T
T
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU25
503
54383
P67
L
Q
G
V
S
L
P
P
P
L
A
D
K
V
E
Baker's Yeast
Sacchar. cerevisiae
P11914
482
53319
D47
S
A
L
G
L
Y
I
D
A
G
S
R
F
E
G
Red Bread Mold
Neurospora crassa
P11913
476
52538
Q41
S
G
T
G
I
K
T
Q
T
T
T
L
K
N
G
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
91.2
86
N.A.
81.7
82
81.3
78.4
N.A.
47.8
32.1
25.5
N.A.
Protein Similarity:
100
N.A.
N.A.
95.2
N.A.
95
90.4
N.A.
90.4
89.9
90.2
88
N.A.
66.3
46.6
44.5
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
6.6
0
6.6
N.A.
53.3
0
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
26.6
13.3
26.6
13.3
N.A.
53.3
0
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
34.4
29.5
Protein Similarity:
N.A.
N.A.
N.A.
48
54.4
49.1
P-Site Identity:
N.A.
N.A.
N.A.
0
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
8
15
0
8
8
8
0
15
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
8
0
0
0
0
0
8
0
0
0
8
0
29
0
% D
% Glu:
15
0
0
36
0
0
43
8
0
0
8
0
0
8
8
% E
% Phe:
0
0
0
0
0
29
0
0
0
0
0
8
8
0
8
% F
% Gly:
0
36
15
15
0
0
0
0
15
15
0
0
8
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
15
0
0
0
0
8
0
0
0
% I
% Lys:
8
8
8
0
29
8
0
0
36
0
15
0
15
0
0
% K
% Leu:
8
8
8
15
8
22
8
0
0
22
8
8
36
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
15
8
8
0
0
0
8
36
% N
% Pro:
8
0
0
0
0
0
8
15
8
0
0
0
0
8
0
% P
% Gln:
0
8
29
0
0
0
0
8
15
0
0
0
0
8
15
% Q
% Arg:
0
8
0
0
8
0
0
0
0
0
8
15
0
0
0
% R
% Ser:
15
0
0
0
15
8
0
8
0
0
8
0
0
15
8
% S
% Thr:
15
8
8
15
15
8
8
36
8
8
43
36
8
8
0
% T
% Val:
0
0
15
15
8
8
0
0
0
36
0
15
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _