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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PMPCA All Species: 36.97
Human Site: Y364 Identified Species: 62.56
UniProt: Q10713 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q10713 NP_055975.1 525 58253 Y364 K G M F S R L Y L N V L N R H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537796 526 58551 Y365 K G M F T R L Y L N V L N R H
Cat Felis silvestris
Mouse Mus musculus Q9DC61 524 58261 Y363 K G M F S R L Y L N V L N R H
Rat Rattus norvegicus P20069 524 58589 Y363 K G M F S R L Y L N V L N R H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521013 513 57132 Y352 K G M F T R L Y L N V L N R Y
Chicken Gallus gallus NP_001006197 519 57529 Y358 K G M F T R L Y L N V L N R H
Frog Xenopus laevis NP_001089466 518 57691 Y357 K G M F T R L Y L N V L N R H
Zebra Danio Brachydanio rerio NP_001007443 517 57513 Y356 K G M F T R L Y L N V L N R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610333 556 61032 Y394 K G M Y S R L Y T K V L N R Y
Honey Bee Apis mellifera XP_624556 358 40406 N199 R L Y T N V L N R Y H W L Y S
Nematode Worm Caenorhab. elegans P98080 471 51717 A312 T H A T S R T A A S R L V Q K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZU25 503 54383 G344 G G G S F S A G G P G K G M H
Baker's Yeast Sacchar. cerevisiae P11914 482 53319 Y323 C V A F N H S Y S D S G I F G
Red Bread Mold Neurospora crassa P11913 476 52538 P317 D K A L G N A P H Q G S K L S
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.1 N.A. 91.2 86 N.A. 81.7 82 81.3 78.4 N.A. 47.8 32.1 25.5 N.A.
Protein Similarity: 100 N.A. N.A. 95.2 N.A. 95 90.4 N.A. 90.4 89.9 90.2 88 N.A. 66.3 46.6 44.5 N.A.
P-Site Identity: 100 N.A. N.A. 93.3 N.A. 100 100 N.A. 86.6 93.3 93.3 93.3 N.A. 73.3 6.6 20 N.A.
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 86.6 20 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.6 34.4 29.5
Protein Similarity: N.A. N.A. N.A. 48 54.4 49.1
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 0
P-Site Similarity: N.A. N.A. N.A. 13.3 26.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 22 0 0 0 15 8 8 0 0 0 0 0 0 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 65 8 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 8 72 8 0 8 0 0 8 8 0 15 8 8 0 8 % G
% His: 0 8 0 0 0 8 0 0 8 0 8 0 0 0 58 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 65 8 0 0 0 0 0 0 0 8 0 8 8 0 8 % K
% Leu: 0 8 0 8 0 0 72 0 58 0 0 72 8 8 0 % L
% Met: 0 0 65 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 15 8 0 8 0 58 0 0 65 0 0 % N
% Pro: 0 0 0 0 0 0 0 8 0 8 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % Q
% Arg: 8 0 0 0 0 72 0 0 8 0 8 0 0 65 0 % R
% Ser: 0 0 0 8 36 8 8 0 8 8 8 8 0 0 15 % S
% Thr: 8 0 0 15 36 0 8 0 8 0 0 0 0 0 0 % T
% Val: 0 8 0 0 0 8 0 0 0 0 65 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 0 8 8 0 0 0 72 0 8 0 0 0 8 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _