Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PMPCA All Species: 15.15
Human Site: Y39 Identified Species: 25.64
UniProt: Q10713 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q10713 NP_055975.1 525 58253 Y39 R F S S G G A Y P N I P L S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537796 526 58551 Y40 Q F S G G G A Y P H V P L S S
Cat Felis silvestris
Mouse Mus musculus Q9DC61 524 58261 Y38 R F S S G A T Y P N I P L S S
Rat Rattus norvegicus P20069 524 58589 Y38 R F S S G A T Y P N I P L S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521013 513 57132 P40 S S P L P G I P T P I F A T V
Chicken Gallus gallus NP_001006197 519 57529 C40 Y P N V S L T C P L P G V P K
Frog Xenopus laevis NP_001089466 518 57691 S38 T Y P S I P L S T P L P K L P
Zebra Danio Brachydanio rerio NP_001007443 517 57513 T38 Y P N V S L S T P L P G I P K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610333 556 61032 V66 N T P S K E I V T H L P P L T
Honey Bee Apis mellifera XP_624556 358 40406
Nematode Worm Caenorhab. elegans P98080 471 51717 S8 M A L R L A V S S A L R P A L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZU25 503 54383 P39 A E T S S S T P A Y L S W L S
Baker's Yeast Sacchar. cerevisiae P11914 482 53319 F19 N I A R T D N F K L S S L A N
Red Bread Mold Neurospora crassa P11913 476 52538 G13 L A L N L A Q G V K A R A G G
Conservation
Percent
Protein Identity: 100 N.A. N.A. 90.1 N.A. 91.2 86 N.A. 81.7 82 81.3 78.4 N.A. 47.8 32.1 25.5 N.A.
Protein Similarity: 100 N.A. N.A. 95.2 N.A. 95 90.4 N.A. 90.4 89.9 90.2 88 N.A. 66.3 46.6 44.5 N.A.
P-Site Identity: 100 N.A. N.A. 73.3 N.A. 86.6 86.6 N.A. 13.3 6.6 13.3 6.6 N.A. 13.3 0 0 N.A.
P-Site Similarity: 100 N.A. N.A. 93.3 N.A. 86.6 86.6 N.A. 20 20 26.6 26.6 N.A. 33.3 0 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.6 34.4 29.5
Protein Similarity: N.A. N.A. N.A. 48 54.4 49.1
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 0
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 8 0 0 29 15 0 8 8 8 0 15 15 0 % A
% Cys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 29 0 0 0 0 0 8 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 8 29 22 0 8 0 0 0 15 0 8 8 % G
% His: 0 0 0 0 0 0 0 0 0 15 0 0 0 0 0 % H
% Ile: 0 8 0 0 8 0 15 0 0 0 29 0 8 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 8 8 0 0 8 0 15 % K
% Leu: 8 0 15 8 15 15 8 0 0 22 29 0 36 22 8 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 15 0 15 8 0 0 8 0 0 22 0 0 0 0 8 % N
% Pro: 0 15 22 0 8 8 0 15 43 15 15 43 15 15 8 % P
% Gln: 8 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % Q
% Arg: 22 0 0 15 0 0 0 0 0 0 0 15 0 0 0 % R
% Ser: 8 8 29 43 22 8 8 15 8 0 8 15 0 29 36 % S
% Thr: 8 8 8 0 8 0 29 8 22 0 0 0 0 8 8 % T
% Val: 0 0 0 15 0 0 8 8 8 0 8 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 15 8 0 0 0 0 0 29 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _