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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PMPCA
All Species:
29.09
Human Site:
Y503
Identified Species:
49.23
UniProt:
Q10713
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q10713
NP_055975.1
525
58253
Y503
D
L
T
D
L
P
T
Y
E
H
I
Q
T
A
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537796
526
58551
Y504
D
L
S
H
L
P
A
Y
E
H
I
Q
A
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC61
524
58261
Y502
D
L
T
D
L
P
T
Y
E
H
I
Q
A
A
L
Rat
Rattus norvegicus
P20069
524
58589
Y502
D
L
T
D
L
P
T
Y
E
H
I
Q
A
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521013
513
57132
Y491
D
L
S
D
L
P
G
Y
E
H
I
Q
A
A
L
Chicken
Gallus gallus
NP_001006197
519
57529
Y497
D
L
T
D
L
P
T
Y
E
H
I
Q
E
A
L
Frog
Xenopus laevis
NP_001089466
518
57691
Y496
D
L
T
E
L
P
D
Y
E
H
I
Q
A
A
L
Zebra Danio
Brachydanio rerio
NP_001007443
517
57513
Y495
D
L
T
E
L
P
S
Y
E
D
I
Q
A
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610333
556
61032
M533
D
I
H
N
L
P
E
M
S
H
I
T
N
A
V
Honey Bee
Apis mellifera
XP_624556
358
40406
Q337
I
P
S
I
R
D
I
Q
A
G
L
I
D
E
Q
Nematode Worm
Caenorhab. elegans
P98080
471
51717
V450
R
D
L
A
A
V
G
V
G
R
T
E
A
F
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZU25
503
54383
T482
K
V
I
S
K
P
L
T
M
G
S
F
G
D
V
Baker's Yeast
Sacchar. cerevisiae
P11914
482
53319
K461
G
D
V
E
N
V
L
K
A
Y
G
L
G
N
S
Red Bread Mold
Neurospora crassa
P11913
476
52538
V455
Q
D
I
A
I
S
A
V
G
S
I
E
G
L
F
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
90.1
N.A.
91.2
86
N.A.
81.7
82
81.3
78.4
N.A.
47.8
32.1
25.5
N.A.
Protein Similarity:
100
N.A.
N.A.
95.2
N.A.
95
90.4
N.A.
90.4
89.9
90.2
88
N.A.
66.3
46.6
44.5
N.A.
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
93.3
93.3
N.A.
80
93.3
80
73.3
N.A.
40
0
0
N.A.
P-Site Similarity:
100
N.A.
N.A.
80
N.A.
93.3
93.3
N.A.
86.6
93.3
86.6
86.6
N.A.
60
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
34.4
29.5
Protein Similarity:
N.A.
N.A.
N.A.
48
54.4
49.1
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
8
0
15
0
15
0
0
0
50
65
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
65
22
0
36
0
8
8
0
0
8
0
0
8
8
0
% D
% Glu:
0
0
0
22
0
0
8
0
58
0
0
15
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
8
% F
% Gly:
8
0
0
0
0
0
15
0
15
15
8
0
22
0
0
% G
% His:
0
0
8
8
0
0
0
0
0
58
0
0
0
0
0
% H
% Ile:
8
8
15
8
8
0
8
0
0
0
72
8
0
0
0
% I
% Lys:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
58
8
0
65
0
15
0
0
0
8
8
0
8
58
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
8
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
0
8
0
0
0
72
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
0
0
0
0
8
0
0
0
58
0
0
8
% Q
% Arg:
8
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
0
22
8
0
8
8
0
8
8
8
0
0
0
8
% S
% Thr:
0
0
43
0
0
0
29
8
0
0
8
8
8
0
0
% T
% Val:
0
8
8
0
0
15
0
15
0
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
58
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _