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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 16.67
Human Site: S1099 Identified Species: 30.56
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 S1099 V L S P L R P S R R H F P R V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 L830 F F P P P M P L S K P V P A T
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 S1098 V L S P L R P S R R H F P R V
Rat Rattus norvegicus O88658 1816 204151 S1216 L N S P P Q P S R R F F P P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 S1098 V L S P L R P S R R H F P R V
Chicken Gallus gallus XP_422660 1772 200700 S1179 V L S P L R P S R R H F P R V
Frog Xenopus laevis Q91784 1226 138905 Q649 E I Q G M K M Q R V Q L M R Q
Zebra Danio Brachydanio rerio XP_695144 1667 189110 L1088 Q K Q P F P P L C K D L I S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 P1080 D F V S R P P P R R M L P P S
Honey Bee Apis mellifera XP_397276 1682 191012 K1073 E Y V R Q P P K R M L P P S I
Nematode Worm Caenorhab. elegans P23678 1584 179603 E1006 K S E Q F N F E R Q N S A L G
Sea Urchin Strong. purpuratus P46871 742 84184 L165 D Q K K R L D L K E R P D T G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 K351 E L K Q M L A K A K T Q I T S
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 20 N.A. 100 53.3 N.A. 100 100 13.3 13.3 N.A. 26.6 20 6.6 0
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 100 66.6 N.A. 100 100 33.3 20 N.A. 26.6 26.6 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 8 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 16 0 0 0 0 0 8 0 0 0 8 0 8 0 0 % D
% Glu: 24 0 8 0 0 0 0 8 0 8 0 0 0 0 0 % E
% Phe: 8 16 0 0 16 0 8 0 0 0 8 39 0 0 0 % F
% Gly: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 16 % G
% His: 0 0 0 0 0 0 0 0 0 0 31 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 16 0 8 % I
% Lys: 8 8 16 8 0 8 0 16 8 24 0 0 0 0 0 % K
% Leu: 8 39 0 0 31 16 0 24 0 0 8 24 0 8 0 % L
% Met: 0 0 0 0 16 8 8 0 0 8 8 0 8 0 0 % M
% Asn: 0 8 0 0 0 8 0 0 0 0 8 0 0 0 0 % N
% Pro: 0 0 8 54 16 24 70 8 0 0 8 16 62 16 8 % P
% Gln: 8 8 16 16 8 8 0 8 0 8 8 8 0 0 8 % Q
% Arg: 0 0 0 8 16 31 0 0 70 47 8 0 0 39 0 % R
% Ser: 0 8 39 8 0 0 0 39 8 0 0 8 0 16 24 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 8 0 0 16 8 % T
% Val: 31 0 16 0 0 0 0 0 0 8 0 8 0 0 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _