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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 15.15
Human Site: S1119 Identified Species: 27.78
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 S1119 P V P A T K L S T L T R P C P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 S850 S K T S L G Q S M S K Y D L L
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 S1118 P V P A T K L S T M T R P S P
Rat Rattus norvegicus O88658 1816 204151 N1236 P V P A T K L N T M N K T S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 S1118 P V P A T K L S T L T R P T A
Chicken Gallus gallus XP_422660 1772 200700 S1199 P V P A T K L S T M T R P S A
Frog Xenopus laevis Q91784 1226 138905 Q669 E K F R T W K Q Q K T K E V I
Zebra Danio Brachydanio rerio XP_695144 1667 189110 P1108 R Q F P R V M P L S K P V P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 G1100 P V R S P K F G P L P C A P T
Honey Bee Apis mellifera XP_397276 1682 191012 S1093 V R S P K F G S V L P S P S T
Nematode Worm Caenorhab. elegans P23678 1584 179603 S1026 K L T F Q Q P S L V I S T P V
Sea Urchin Strong. purpuratus P46871 742 84184 S185 L S S F V T K S V K E I E H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 Q371 V N L E S E V Q V W R G G E T
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 86.6 53.3 N.A. 86.6 80 13.3 0 N.A. 26.6 20 6.6 6.6
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 93.3 73.3 N.A. 86.6 86.6 20 6.6 N.A. 33.3 20 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 39 0 0 0 0 0 0 0 0 8 0 24 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % D
% Glu: 8 0 0 8 0 8 0 0 0 0 8 0 16 8 0 % E
% Phe: 0 0 16 16 0 8 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 8 8 0 0 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 8 % I
% Lys: 8 16 0 0 8 47 16 0 0 16 16 16 0 0 0 % K
% Leu: 8 8 8 0 8 0 39 0 16 31 0 0 0 8 16 % L
% Met: 0 0 0 0 0 0 8 0 8 24 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 0 8 0 0 0 0 % N
% Pro: 47 0 39 16 8 0 8 8 8 0 16 8 39 24 16 % P
% Gln: 0 8 0 0 8 8 8 16 8 0 0 0 0 0 0 % Q
% Arg: 8 8 8 8 8 0 0 0 0 0 8 31 0 0 0 % R
% Ser: 8 8 16 16 8 0 0 62 0 16 0 16 0 31 0 % S
% Thr: 0 0 16 0 47 8 0 0 39 0 39 0 16 8 24 % T
% Val: 16 47 0 0 8 8 8 0 24 8 0 0 8 8 16 % V
% Trp: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _