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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 23.03
Human Site: S1351 Identified Species: 42.22
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 S1351 R R R V L D T S V A Y V R G E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 G1078 T S V A Y V R G E E N L A G W
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 S1356 R R R V L D T S V A Y V R G E
Rat Rattus norvegicus O88658 1816 204151 S1468 R R K V L D T S V A Y V R G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 S1350 R R R V L D T S V A Y V R G E
Chicken Gallus gallus XP_422660 1772 200700 S1431 R R R V L D T S V A Y V R G E
Frog Xenopus laevis Q91784 1226 138905 V897 V K Q N R A H V A D L Q K N I
Zebra Danio Brachydanio rerio XP_695144 1667 189110 G1336 L C H L A D I G S P G M Q R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 S1331 Q R R V L D T S S T Y V R G E
Honey Bee Apis mellifera XP_397276 1682 191012 T1325 R V L D T S S T Y V R G E E N
Nematode Worm Caenorhab. elegans P23678 1584 179603 G1254 L K D G S D S G S P G A I R R
Sea Urchin Strong. purpuratus P46871 742 84184 E413 D E E E M Y K E S Q Q K L E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 D599 F E I S S A G D A I P P E D I
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 100 93.3 N.A. 100 100 0 6.6 N.A. 80 6.6 6.6 6.6
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 100 100 N.A. 100 100 20 26.6 N.A. 86.6 20 20 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 8 16 0 0 16 39 0 8 8 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 8 0 62 0 8 0 8 0 0 0 8 0 % D
% Glu: 0 16 8 8 0 0 0 8 8 8 0 0 16 16 54 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 0 0 8 24 0 0 16 8 0 54 0 % G
% His: 0 0 8 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 8 0 0 8 0 0 8 0 16 % I
% Lys: 0 16 8 0 0 0 8 0 0 0 0 8 8 0 0 % K
% Leu: 16 0 8 8 47 0 0 0 0 0 8 8 8 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 8 0 0 0 0 0 0 8 0 0 8 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 16 8 8 0 0 0 % P
% Gln: 8 0 8 0 0 0 0 0 0 8 8 8 8 0 0 % Q
% Arg: 47 47 39 0 8 0 8 0 0 0 8 0 47 16 16 % R
% Ser: 0 8 0 8 16 8 16 47 31 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 8 0 47 8 0 8 0 0 0 0 0 % T
% Val: 8 8 8 47 0 8 0 8 39 8 0 47 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % W
% Tyr: 0 0 0 0 8 8 0 0 8 0 47 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _