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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 11.82
Human Site: S1413 Identified Species: 21.67
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 S1413 R P V P E A L S P A F S E D S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 S1140 S L S P S L S S G T L S T S T
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 S1418 R P G P E V L S P A S S E D S
Rat Rattus norvegicus O88658 1816 204151 L1530 P K S M S D S L S P S L S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 S1412 R S G Q E T L S P C S S E D S
Chicken Gallus gallus XP_422660 1772 200700 S1493 R L G L E S L S P C S S E D S
Frog Xenopus laevis Q91784 1226 138905 I959 E E L P A E E I T E R E K Q L
Zebra Danio Brachydanio rerio XP_695144 1667 189110 R1398 T R H Y L L L R E K L E A S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 T1393 N P N P T T K T E K D V C N L
Honey Bee Apis mellifera XP_397276 1682 191012 D1387 F C N K I S H D F T K S E K D
Nematode Worm Caenorhab. elegans P23678 1584 179603 R1316 V R L F L R L R D R L K G K K
Sea Urchin Strong. purpuratus P46871 742 84184 G475 E S K L L V G G K S I V D H T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 N661 H E E L L S R N L T E A D K E
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 20 N.A. 80 0 N.A. 60 60 6.6 6.6 N.A. 13.3 13.3 6.6 0
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 80 0 N.A. 60 66.6 20 6.6 N.A. 26.6 20 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 26.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 0 0 0 16 0 8 8 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 16 0 0 8 0 0 % C
% Asp: 0 0 0 0 0 8 0 8 8 0 8 0 16 31 8 % D
% Glu: 16 16 8 0 31 8 8 0 16 8 8 16 39 0 8 % E
% Phe: 8 0 0 8 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 0 0 24 0 0 0 8 8 8 0 0 0 8 0 8 % G
% His: 8 0 8 0 0 0 8 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 0 8 0 0 8 0 0 8 0 0 0 0 % I
% Lys: 0 8 8 8 0 0 8 0 8 16 8 8 8 24 8 % K
% Leu: 0 16 16 24 31 16 47 8 8 0 24 8 0 0 24 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 16 0 0 0 0 8 0 0 0 0 0 8 0 % N
% Pro: 8 24 0 39 0 0 0 0 31 8 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 31 16 0 0 0 8 8 16 0 8 8 0 0 0 0 % R
% Ser: 8 16 16 0 16 24 16 39 8 8 31 47 8 24 31 % S
% Thr: 8 0 0 0 8 16 0 8 8 24 0 0 8 0 16 % T
% Val: 8 0 8 0 0 16 0 0 0 0 0 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _