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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 23.03
Human Site: S1681 Identified Species: 42.22
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 S1681 G T I R S K L S R R R S A Q M
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 N1399 N D W L Y A F N P L L A G T I
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 S1686 G T I R S K L S R R R S A Q M
Rat Rattus norvegicus O88658 1816 204151 S1807 G T I R S K L S R R C P S Q P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 S1679 G T I R S K L S R R R T A Q M
Chicken Gallus gallus XP_422660 1772 200700 S1763 G S I R S K L S R R R T A Q M
Frog Xenopus laevis Q91784 1226 138905 G1218 S N T S F F S G C S A I T E D
Zebra Danio Brachydanio rerio XP_695144 1667 189110 S1658 G T I R S K L S R R K S G Q M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 T1660 T A S Q I Q A T N A A N A N S
Honey Bee Apis mellifera XP_397276 1682 191012 A1653 G Q I R S K L A R K G P A A T
Nematode Worm Caenorhab. elegans P23678 1584 179603 P1575 N G T T L K S P T S S S S I A
Sea Urchin Strong. purpuratus P46871 742 84184 P734 G S N S Q L Y P Q A R G L I Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 R920 Q N P P E N K R S S W F F Q K
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 73.3 N.A. 93.3 86.6 0 86.6 N.A. 6.6 53.3 13.3 13.3
P-Site Similarity: 100 N.A. N.A. 20 N.A. 100 80 N.A. 100 100 6.6 93.3 N.A. 33.3 66.6 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 6.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 8 8 8 0 16 16 8 47 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % E
% Phe: 0 0 0 0 8 8 8 0 0 0 0 8 8 0 0 % F
% Gly: 62 8 0 0 0 0 0 8 0 0 8 8 16 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 54 0 8 0 0 0 0 0 0 8 0 16 8 % I
% Lys: 0 0 0 0 0 62 8 0 0 8 8 0 0 0 8 % K
% Leu: 0 0 0 8 8 8 54 0 0 8 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 39 % M
% Asn: 16 16 8 0 0 8 0 8 8 0 0 8 0 8 0 % N
% Pro: 0 0 8 8 0 0 0 16 8 0 0 16 0 0 8 % P
% Gln: 8 8 0 8 8 8 0 0 8 0 0 0 0 54 8 % Q
% Arg: 0 0 0 54 0 0 0 8 54 47 39 0 0 0 0 % R
% Ser: 8 16 8 16 54 0 16 47 8 24 8 31 16 0 8 % S
% Thr: 8 39 16 8 0 0 0 8 8 0 0 16 8 8 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _