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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 23.94
Human Site: S669 Identified Species: 43.89
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 S669 Q Q R L D Y E S K L E A L Q K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 P425 T H E D K P F P R T V V A V E
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 S669 Q Q R L D Y E S K L E A L Q K
Rat Rattus norvegicus O88658 1816 204151 S709 Q Q R L D Y E S K L Q A L Q K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 S669 Q Q R L D Y E S K L E A L Q K
Chicken Gallus gallus XP_422660 1772 200700 S750 Q Q R L D Y E S K L E A L Q K
Frog Xenopus laevis Q91784 1226 138905 S244 H L V D L A G S E R Q K K T K
Zebra Danio Brachydanio rerio XP_695144 1667 189110 S669 Q Q R L D Y E S K L E A L Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 A655 E Q R K T Y E A R I D A L Q K
Honey Bee Apis mellifera XP_397276 1682 191012 A653 E Q R K S Y E A R I D A L Q R
Nematode Worm Caenorhab. elegans P23678 1584 179603 L600 L D K Q G I D L K A D M E K K
Sea Urchin Strong. purpuratus P46871 742 84184
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 0 N.A. 100 93.3 N.A. 100 100 13.3 100 N.A. 53.3 46.6 13.3 0
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 100 100 N.A. 100 100 26.6 100 N.A. 86.6 86.6 40 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 16 0 8 0 62 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 16 47 0 8 0 0 0 24 0 0 0 0 % D
% Glu: 16 0 8 0 0 0 62 0 8 0 39 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % G
% His: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 16 0 0 0 0 0 % I
% Lys: 0 0 8 16 8 0 0 0 54 0 0 8 8 8 70 % K
% Leu: 8 8 0 47 8 0 0 8 0 47 0 0 62 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % P
% Gln: 47 62 0 8 0 0 0 0 0 0 16 0 0 62 0 % Q
% Arg: 0 0 62 0 0 0 0 0 24 8 0 0 0 0 8 % R
% Ser: 0 0 0 0 8 0 0 54 0 0 0 0 0 0 0 % S
% Thr: 8 0 0 0 8 0 0 0 0 8 0 0 0 8 0 % T
% Val: 0 0 8 0 0 0 0 0 0 0 8 8 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 62 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _