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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 24.24
Human Site: T1350 Identified Species: 44.44
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 T1350 R R R R V L D T S V A Y V R G
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 R1077 D T S V A Y V R G E E N L A G
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 T1355 R R R R V L D T S V A Y V R G
Rat Rattus norvegicus O88658 1816 204151 T1467 R R R K V L D T S V A Y V R G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 T1349 R R R R V L D T S V A Y V R G
Chicken Gallus gallus XP_422660 1772 200700 T1430 R R R R V L D T S V A Y V R G
Frog Xenopus laevis Q91784 1226 138905 H896 S V K Q N R A H V A D L Q K N
Zebra Danio Brachydanio rerio XP_695144 1667 189110 I1335 S L C H L A D I G S P G M Q R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 T1330 R Q R R V L D T S S T Y V R G
Honey Bee Apis mellifera XP_397276 1682 191012 S1324 R R V L D T S S T Y V R G E E
Nematode Worm Caenorhab. elegans P23678 1584 179603 S1253 C L K D G S D S G S P G A I R
Sea Urchin Strong. purpuratus P46871 742 84184 K412 M D E E E M Y K E S Q Q K L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 G598 L F E I S S A G D A I P P E D
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 100 93.3 N.A. 100 100 0 6.6 N.A. 80 13.3 6.6 0
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 100 100 N.A. 100 100 20 26.6 N.A. 86.6 26.6 20 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 8 16 0 0 16 39 0 8 8 0 % A
% Cys: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 8 8 0 62 0 8 0 8 0 0 0 8 % D
% Glu: 0 0 16 8 8 0 0 0 8 8 8 0 0 16 16 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 8 0 0 8 24 0 0 16 8 0 54 % G
% His: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 8 0 0 8 0 0 8 0 % I
% Lys: 0 0 16 8 0 0 0 8 0 0 0 0 8 8 0 % K
% Leu: 8 16 0 8 8 47 0 0 0 0 0 8 8 8 0 % L
% Met: 8 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 16 8 8 0 0 % P
% Gln: 0 8 0 8 0 0 0 0 0 0 8 8 8 8 0 % Q
% Arg: 54 47 47 39 0 8 0 8 0 0 0 8 0 47 16 % R
% Ser: 16 0 8 0 8 16 8 16 47 31 0 0 0 0 0 % S
% Thr: 0 8 0 0 0 8 0 47 8 0 8 0 0 0 0 % T
% Val: 0 8 8 8 47 0 8 0 8 39 8 0 47 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 8 0 0 8 0 47 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _