Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF1A All Species: 22.12
Human Site: Y1354 Identified Species: 40.56
UniProt: Q12756 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12756 NP_004312.2 1690 191064 Y1354 V L D T S V A Y V R G E E N L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_536743 1407 158778 N1081 A Y V R G E E N L A G W R P R
Cat Felis silvestris
Mouse Mus musculus P33173 1695 191706 Y1359 V L D T S V A Y V R G E E N L
Rat Rattus norvegicus O88658 1816 204151 Y1471 V L D T S V A Y V R G E E N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513785 1688 191581 Y1353 V L D T S V A Y V R G E E N L
Chicken Gallus gallus XP_422660 1772 200700 Y1434 V L D T S V A Y V R G E E N L
Frog Xenopus laevis Q91784 1226 138905 L900 N R A H V A D L Q K N I F E E
Zebra Danio Brachydanio rerio XP_695144 1667 189110 G1339 L A D I G S P G M Q R R R R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A1ZAJ2 1670 189326 Y1334 V L D T S S T Y V R G E E N L
Honey Bee Apis mellifera XP_397276 1682 191012 R1328 D T S S T Y V R G E E N L H G
Nematode Worm Caenorhab. elegans P23678 1584 179603 G1257 G S D S G S P G A I R R Q R R
Sea Urchin Strong. purpuratus P46871 742 84184 Q416 E M Y K E S Q Q K L E E E K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P48467 928 102392 P602 S S A G D A I P P E D I K A L
Conservation
Percent
Protein Identity: 100 N.A. N.A. 41 N.A. 97 68.8 N.A. 93.4 87.6 23.3 81.5 N.A. 57.4 59.8 51.7 22.1
Protein Similarity: 100 N.A. N.A. 56.6 N.A. 98.2 79 N.A. 96.2 91 40.5 89.2 N.A. 73 75 68.1 32
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 100 100 N.A. 100 100 0 6.6 N.A. 86.6 0 6.6 13.3
P-Site Similarity: 100 N.A. N.A. 13.3 N.A. 100 100 N.A. 100 100 6.6 26.6 N.A. 86.6 20 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 22.3
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 35.6
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 13.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 16 0 0 16 39 0 8 8 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 62 0 8 0 8 0 0 0 8 0 0 0 0 % D
% Glu: 8 0 0 0 8 8 8 0 0 16 16 54 54 8 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 0 8 24 0 0 16 8 0 54 0 0 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 8 0 % H
% Ile: 0 0 0 8 0 0 8 0 0 8 0 16 0 0 0 % I
% Lys: 0 0 0 8 0 0 0 0 8 8 0 0 8 8 0 % K
% Leu: 8 47 0 0 0 0 0 8 8 8 0 0 8 0 54 % L
% Met: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 8 8 0 47 0 % N
% Pro: 0 0 0 0 0 0 16 8 8 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 8 8 8 8 0 0 8 0 0 % Q
% Arg: 0 8 0 8 0 0 0 8 0 47 16 16 16 16 24 % R
% Ser: 8 16 8 16 47 31 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 8 0 47 8 0 8 0 0 0 0 0 0 0 0 % T
% Val: 47 0 8 0 8 39 8 0 47 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % W
% Tyr: 0 8 8 0 0 8 0 47 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _