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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA0195 All Species: 16.67
Human Site: S515 Identified Species: 40.74
UniProt: Q12767 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12767 NP_055553.3 1356 151151 S515 R S K H P S G S N V S F S R D
Chimpanzee Pan troglodytes XP_511677 1356 151067 S515 R S K H P S G S N V S F S R D
Rhesus Macaque Macaca mulatta XP_001096655 1356 151118 S515 R S K H P S G S N V S F S R D
Dog Lupus familis XP_540432 1409 156624 S568 H G R N K H P S G S N V S F S
Cat Felis silvestris
Mouse Mus musculus Q7TSH8 1360 151777 S519 R S K H P S G S N V S F S R D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001335587 1371 152839 G532 T R S K H P S G S N V S F S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_722974 1449 162236 F520 T H E H Y A Q F C G H V T A V
Honey Bee Apis mellifera XP_396078 1377 157293 T453 R N A T Q Y Q T Q T D D S K Q
Nematode Worm Caenorhab. elegans NP_491390 1184 133375 N382 K Q L L L E I N W R L I P D E
Sea Urchin Strong. purpuratus XP_001202048 1453 162456 H521 K K R I P A P H T L S V L V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.2 92.1 N.A. 95.2 N.A. N.A. N.A. N.A. N.A. 68.3 N.A. 26.2 27.2 24.4 21.6
Protein Similarity: 100 99.7 99.7 94.3 N.A. 97.2 N.A. N.A. N.A. N.A. N.A. 79.6 N.A. 43.8 45.6 42.3 39.3
P-Site Identity: 100 100 100 13.3 N.A. 100 N.A. N.A. N.A. N.A. N.A. 0 N.A. 6.6 13.3 0 13.3
P-Site Similarity: 100 100 100 33.3 N.A. 100 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. 26.6 33.3 20 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 20 0 0 0 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 10 0 10 40 % D
% Glu: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 40 10 10 0 % F
% Gly: 0 10 0 0 0 0 40 10 10 10 0 0 0 0 0 % G
% His: 10 10 0 50 10 10 0 10 0 0 10 0 0 0 10 % H
% Ile: 0 0 0 10 0 0 10 0 0 0 0 10 0 0 0 % I
% Lys: 20 10 40 10 10 0 0 0 0 0 0 0 0 10 0 % K
% Leu: 0 0 10 10 10 0 0 0 0 10 10 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 10 0 0 0 10 40 10 10 0 0 0 0 % N
% Pro: 0 0 0 0 50 10 20 0 0 0 0 0 10 0 0 % P
% Gln: 0 10 0 0 10 0 20 0 10 0 0 0 0 0 20 % Q
% Arg: 50 10 20 0 0 0 0 0 0 10 0 0 0 40 0 % R
% Ser: 0 40 10 0 0 40 10 50 10 10 50 10 60 10 10 % S
% Thr: 20 0 0 10 0 0 0 10 10 10 0 0 10 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 40 10 30 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _