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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NUP160 All Species: 4.55
Human Site: S181 Identified Species: 9.09
UniProt: Q12769 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12769 NP_056046.1 1436 162121 S181 R S E L V V D S Q M Q S I F T
Chimpanzee Pan troglodytes XP_001170076 1436 162030 S181 K S E L V V D S Q M Q S I F T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_540738 1363 153628 I175 L K L P P Y D I P G M V S V V
Cat Felis silvestris
Mouse Mus musculus Q9Z0W3 1402 158213 P174 S Q L I P S V P G L S P G S T
Rat Rattus norvegicus NP_001101214 1379 155482 G175 Q L I P T V P G L S P S S T T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509993 1264 143172 A103 L T G W M S T A I R G D Q G P
Chicken Gallus gallus XP_001232607 1223 137633 V63 L L V T V Q S V H R V L L P H
Frog Xenopus laevis NP_001084965 925 104748
Zebra Danio Brachydanio rerio NP_956956 1203 135028 A43 S S G G V K Y A D S A G G F S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VKJ3 1411 160257 Q181 A A V S Y L T Q D S Q S A Y F
Honey Bee Apis mellifera XP_001121192 1348 154633 A175 N S P V P H A A A S W F I P P
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203261 1166 129557
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 N.A. 86.4 N.A. 90.5 89.8 N.A. 77.3 60.3 41.3 53.2 N.A. 28.2 32.1 N.A. 27
Protein Similarity: 100 99.8 N.A. 90.6 N.A. 94.2 93.3 N.A. 83.5 71.5 52.7 66.1 N.A. 49.3 53.2 N.A. 44
P-Site Identity: 100 93.3 N.A. 6.6 N.A. 6.6 20 N.A. 0 6.6 0 20 N.A. 13.3 13.3 N.A. 0
P-Site Similarity: 100 100 N.A. 6.6 N.A. 20 26.6 N.A. 20 13.3 0 33.3 N.A. 33.3 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 0 0 0 0 9 25 9 0 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 25 0 17 0 0 9 0 0 0 % D
% Glu: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 9 0 25 9 % F
% Gly: 0 0 17 9 0 0 0 9 9 9 9 9 17 9 0 % G
% His: 0 0 0 0 0 9 0 0 9 0 0 0 0 0 9 % H
% Ile: 0 0 9 9 0 0 0 9 9 0 0 0 25 0 0 % I
% Lys: 9 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % K
% Leu: 25 17 17 17 0 9 0 0 9 9 0 9 9 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 17 9 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 9 17 25 0 9 9 9 0 9 9 0 17 17 % P
% Gln: 9 9 0 0 0 9 0 9 17 0 25 0 9 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % R
% Ser: 17 34 0 9 0 17 9 17 0 34 9 34 17 9 9 % S
% Thr: 0 9 0 9 9 0 17 0 0 0 0 0 0 9 34 % T
% Val: 0 0 17 9 34 25 9 9 0 0 9 9 0 9 9 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 9 9 9 0 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _