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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCAP
All Species:
20.91
Human Site:
S494
Identified Species:
46
UniProt:
Q12770
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12770
NP_036367.2
1279
139729
S494
T
I
T
L
Q
P
S
S
F
R
N
L
R
L
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001100342
1223
133661
K466
E
A
C
L
P
S
A
K
P
V
G
Q
P
T
R
Dog
Lupus familis
XP_541898
1261
137697
S494
T
I
T
L
Q
P
S
S
F
R
N
L
R
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6GQT6
1276
139592
S494
T
I
T
L
Q
P
S
S
F
R
N
L
R
L
P
Rat
Rattus norvegicus
A2RRU4
1276
139480
S494
T
I
T
L
Q
P
S
S
F
R
N
L
R
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231540
1275
140135
S494
T
I
T
L
Q
P
S
S
F
R
N
L
R
L
P
Frog
Xenopus laevis
A0JPH4
1311
145343
S488
P
H
T
I
T
L
Q
S
L
R
N
L
R
L
P
Zebra Danio
Brachydanio rerio
XP_686585
1245
136420
A485
T
I
T
L
Q
T
P
A
F
R
N
L
R
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788277
1276
142477
L516
S
D
F
M
L
Q
M
L
L
F
S
T
I
L
A
Honey Bee
Apis mellifera
XP_394934
1329
150443
P483
L
N
G
L
S
N
G
P
T
T
V
I
A
P
N
Nematode Worm
Caenorhab. elegans
NP_001022051
1087
124644
L341
E
V
Y
P
Y
I
A
L
I
M
G
L
E
N
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94
92
N.A.
91.9
92.4
N.A.
N.A.
59.1
69.3
68.5
N.A.
29.3
33.1
23
N.A.
Protein Similarity:
100
N.A.
94.5
93.6
N.A.
94.6
95.1
N.A.
N.A.
67.6
79.5
77.9
N.A.
47.2
53.7
40.6
N.A.
P-Site Identity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
N.A.
100
53.3
80
N.A.
6.6
6.6
6.6
N.A.
P-Site Similarity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
N.A.
100
60
86.6
N.A.
26.6
13.3
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
19
10
0
0
0
0
10
0
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
19
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
55
10
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
0
0
19
0
0
0
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
55
0
10
0
10
0
0
10
0
0
10
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
73
10
10
0
19
19
0
0
73
0
73
0
% L
% Met:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
64
0
0
10
10
% N
% Pro:
10
0
0
10
10
46
10
10
10
0
0
0
10
10
64
% P
% Gln:
0
0
0
0
55
10
10
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
64
0
0
64
0
10
% R
% Ser:
10
0
0
0
10
10
46
55
0
0
10
0
0
0
0
% S
% Thr:
55
0
64
0
10
10
0
0
10
10
0
10
0
10
10
% T
% Val:
0
10
0
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _