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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SCAP All Species: 22.42
Human Site: Y85 Identified Species: 49.33
UniProt: Q12770 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12770 NP_036367.2 1279 139729 Y85 P T E Q P E W Y V G A P V A Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001100342 1223 133661 Y85 P T E Q P E W Y V G A P V A Y
Dog Lupus familis XP_541898 1261 137697 Y85 P S E R P E W Y V G A P V A Y
Cat Felis silvestris
Mouse Mus musculus Q6GQT6 1276 139592 Y85 P S E Q P E W Y V G A P V A Y
Rat Rattus norvegicus A2RRU4 1276 139480 Y85 P S E Q P E W Y V G A P V A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231540 1275 140135 Y85 L S E R P D W Y V G A P V A Y
Frog Xenopus laevis A0JPH4 1311 145343 G85 D Q P D W Y V G L P V A F I Q
Zebra Danio Brachydanio rerio XP_686585 1245 136420 P85 R P D W Y R G P P V A Y I Q Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_788277 1276 142477 P133 T T P Q E P H P S G E P W P P
Honey Bee Apis mellifera XP_394934 1329 150443 W85 L R V G V V P W T E E L T L M
Nematode Worm Caenorhab. elegans NP_001022051 1087 124644
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 94 92 N.A. 91.9 92.4 N.A. N.A. 59.1 69.3 68.5 N.A. 29.3 33.1 23 N.A.
Protein Similarity: 100 N.A. 94.5 93.6 N.A. 94.6 95.1 N.A. N.A. 67.6 79.5 77.9 N.A. 47.2 53.7 40.6 N.A.
P-Site Identity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. N.A. 73.3 0 6.6 N.A. 26.6 0 0 N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. 93.3 6.6 20 N.A. 26.6 6.6 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 64 10 0 55 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 10 10 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 55 0 10 46 0 0 0 10 19 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 10 0 0 10 10 0 64 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 19 0 0 0 0 0 0 0 10 0 0 10 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 46 10 19 0 55 10 10 19 10 10 0 64 0 10 10 % P
% Gln: 0 10 0 46 0 0 0 0 0 0 0 0 0 10 19 % Q
% Arg: 10 10 0 19 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 37 0 0 0 0 0 0 10 0 0 0 0 0 0 % S
% Thr: 10 28 0 0 0 0 0 0 10 0 0 0 10 0 0 % T
% Val: 0 0 10 0 10 10 10 0 55 10 10 0 55 0 0 % V
% Trp: 0 0 0 10 10 0 55 10 0 0 0 0 10 0 0 % W
% Tyr: 0 0 0 0 10 10 0 55 0 0 0 10 0 0 55 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _