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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL3
All Species:
4.24
Human Site:
S251
Identified Species:
10.37
UniProt:
Q12788
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12788
NP_006444.2
808
89035
S251
L
L
P
E
E
P
V
S
Q
L
G
V
K
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082569
888
97459
S334
L
L
P
E
E
P
V
S
Q
L
G
V
K
S
S
Dog
Lupus familis
XP_547184
801
88352
L250
P
E
E
L
V
P
K
L
D
V
K
S
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4J7
801
88247
P251
L
L
P
E
Q
P
A
P
A
L
G
V
K
S
S
Rat
Rattus norvegicus
Q5U2W5
800
88353
L251
L
L
P
E
E
P
A
L
A
L
G
V
K
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506690
757
82561
H248
G
V
K
S
G
G
L
H
F
L
T
A
G
S
R
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610526
787
88518
D254
L
K
V
L
P
L
Y
D
E
L
E
G
V
V
Y
Honey Bee
Apis mellifera
XP_001120493
781
87939
L258
I
I
S
K
N
L
S
L
P
F
Y
N
K
D
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002319254
913
100555
G317
P
I
Y
F
V
T
V
G
E
R
G
I
V
R
I
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05946
817
91013
G254
G
F
L
K
D
G
D
G
K
R
I
I
Y
T
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.7
88.1
N.A.
88.3
88.2
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
32.2
38.4
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
93.4
N.A.
94.1
93.5
N.A.
78
N.A.
N.A.
N.A.
N.A.
53.8
59.2
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
13.3
N.A.
66.6
66.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
20
N.A.
73.3
73.3
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
20
26.6
N.A.
N.A.
Percent
Protein Identity:
35.2
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
53
N.A.
N.A.
N.A.
51.9
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
20
0
20
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
10
10
10
0
0
0
0
10
0
% D
% Glu:
0
10
10
40
30
0
0
0
20
0
10
0
0
0
10
% E
% Phe:
0
10
0
10
0
0
0
0
10
10
0
0
0
0
0
% F
% Gly:
20
0
0
0
10
20
0
20
0
0
50
10
10
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
10
20
0
0
0
0
0
0
0
0
10
20
0
0
10
% I
% Lys:
0
10
10
20
0
0
10
0
10
0
10
0
60
0
0
% K
% Leu:
50
40
10
20
0
20
10
30
0
60
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
20
0
40
0
10
50
0
10
10
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
20
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
20
0
0
0
10
10
% R
% Ser:
0
0
10
10
0
0
10
20
0
0
0
10
0
40
30
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
0
% T
% Val:
0
10
10
0
20
0
30
0
0
10
0
40
20
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
10
0
0
0
10
0
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _