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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL3 All Species: 13.03
Human Site: S348 Identified Species: 31.85
UniProt: Q12788 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12788 NP_006444.2 808 89035 S348 R F L G P E D S H V V V A S N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082569 888 97459 S431 R F L G P E D S H V I V A S N
Dog Lupus familis XP_547184 801 88352 I347 L G P E D S H I V V A S N S P
Cat Felis silvestris
Mouse Mus musculus Q8C4J7 801 88247 S348 R F L G P S D S H I V V A S N
Rat Rattus norvegicus Q5U2W5 800 88353 S348 R F L G P N D S H I I V A S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506690 757 82561 L345 E V L D V R F L G P D D S H I
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610526 787 88518 R351 C F M G E H D R Y L A V A T N
Honey Bee Apis mellifera XP_001120493 781 87939 V355 S D E I L D I V F L G D N E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002319254 913 100555 K414 R F L G E E E K F L A V A T N
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05946 817 91013 N351 R Y V G P E L N K L A L A T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.7 88.1 N.A. 88.3 88.2 N.A. 65.8 N.A. N.A. N.A. N.A. 32.2 38.4 N.A. N.A.
Protein Similarity: 100 N.A. 89.3 93.4 N.A. 94.1 93.5 N.A. 78 N.A. N.A. N.A. N.A. 53.8 59.2 N.A. N.A.
P-Site Identity: 100 N.A. 93.3 13.3 N.A. 86.6 80 N.A. 6.6 N.A. N.A. N.A. N.A. 40 0 N.A. N.A.
P-Site Similarity: 100 N.A. 100 13.3 N.A. 93.3 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. 66.6 20 N.A. N.A.
Percent
Protein Identity: 35.2 N.A. N.A. N.A. 31.4 N.A.
Protein Similarity: 53 N.A. N.A. N.A. 51.9 N.A.
P-Site Identity: 53.3 N.A. N.A. N.A. 40 N.A.
P-Site Similarity: 73.3 N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 40 0 70 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 10 10 10 50 0 0 0 10 20 0 0 0 % D
% Glu: 10 0 10 10 20 40 10 0 0 0 0 0 0 10 0 % E
% Phe: 0 60 0 0 0 0 10 0 20 0 0 0 0 0 0 % F
% Gly: 0 10 0 70 0 0 0 0 10 0 10 0 0 0 0 % G
% His: 0 0 0 0 0 10 10 0 40 0 0 0 0 10 0 % H
% Ile: 0 0 0 10 0 0 10 10 0 20 20 0 0 0 10 % I
% Lys: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 0 % K
% Leu: 10 0 60 0 10 0 10 10 0 40 0 10 0 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 10 0 0 0 0 20 0 70 % N
% Pro: 0 0 10 0 50 0 0 0 0 10 0 0 0 0 10 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 60 0 0 0 0 10 0 10 0 0 0 0 0 0 0 % R
% Ser: 10 0 0 0 0 20 0 40 0 0 0 10 10 50 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 30 0 % T
% Val: 0 10 10 0 10 0 0 10 10 30 20 60 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _