KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL3
All Species:
12.42
Human Site:
S457
Identified Species:
30.37
UniProt:
Q12788
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12788
NP_006444.2
808
89035
S457
P
L
P
K
A
L
L
S
K
N
T
A
P
D
N
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082569
888
97459
S540
P
L
P
K
A
L
L
S
K
N
T
A
P
D
N
Dog
Lupus familis
XP_547184
801
88352
S454
P
I
P
E
A
L
L
S
K
G
T
A
P
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4J7
801
88247
A457
P
L
P
E
A
L
L
A
K
S
T
A
A
D
S
Rat
Rattus norvegicus
Q5U2W5
800
88353
S457
P
L
P
E
A
L
P
S
K
N
T
A
S
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506690
757
82561
V448
T
G
S
Q
D
C
T
V
K
L
W
P
L
A
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610526
787
88518
L456
G
S
M
K
V
W
Q
L
V
R
S
K
E
D
R
Honey Bee
Apis mellifera
XP_001120493
781
87939
L467
L
C
L
K
L
W
N
L
Q
N
D
I
E
F
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002319254
913
100555
D519
T
I
K
V
W
S
L
D
G
I
S
D
D
A
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05946
817
91013
P469
T
I
K
K
W
I
I
P
K
P
T
A
S
M
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.7
88.1
N.A.
88.3
88.2
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
32.2
38.4
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
93.4
N.A.
94.1
93.5
N.A.
78
N.A.
N.A.
N.A.
N.A.
53.8
59.2
N.A.
N.A.
P-Site Identity:
100
N.A.
100
73.3
N.A.
66.6
73.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
80
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
20
N.A.
N.A.
Percent
Protein Identity:
35.2
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
53
N.A.
N.A.
N.A.
51.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
50
0
0
10
0
0
0
60
10
20
0
% A
% Cys:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
10
0
0
10
10
10
60
20
% D
% Glu:
0
0
0
30
0
0
0
0
0
0
0
0
20
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
10
10
0
0
0
0
0
0
10
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
30
0
0
0
10
10
0
0
10
0
10
0
0
0
% I
% Lys:
0
0
20
50
0
0
0
0
70
0
0
10
0
0
20
% K
% Leu:
10
40
10
0
10
50
50
20
0
10
0
0
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
10
0
0
40
0
0
0
0
20
% N
% Pro:
50
0
50
0
0
0
10
10
0
10
0
10
30
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% R
% Ser:
0
10
10
0
0
10
0
40
0
10
20
0
20
0
20
% S
% Thr:
30
0
0
0
0
0
10
0
0
0
60
0
0
0
0
% T
% Val:
0
0
0
10
10
0
0
10
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
20
20
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _