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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TBL3 All Species: 30.61
Human Site: S580 Identified Species: 74.81
UniProt: Q12788 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12788 NP_006444.2 808 89035 S580 S R G T Q L L S S G S D G L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082569 888 97459 S663 S R G T Q L L S S G S D G L V
Dog Lupus familis XP_547184 801 88352 S577 S R G T Q L L S S G S D G L V
Cat Felis silvestris
Mouse Mus musculus Q8C4J7 801 88247 S580 S R G S Q L L S S G S D G L L
Rat Rattus norvegicus Q5U2W5 800 88353 S580 S R G A Q L L S S G S D G L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506690 757 82561 S570 V L K V T F V S R G T Q L L S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610526 787 88518 A579 H G K F I I S A A S D G L L K
Honey Bee Apis mellifera XP_001120493 781 87939 T589 S R G M Q I I T A S G D G L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002319254 913 100555 S642 T R G S Q F V S C G A D G L V
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q05946 817 91013 S592 N K Q K Q L I S C G A D G L I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.7 88.1 N.A. 88.3 88.2 N.A. 65.8 N.A. N.A. N.A. N.A. 32.2 38.4 N.A. N.A.
Protein Similarity: 100 N.A. 89.3 93.4 N.A. 94.1 93.5 N.A. 78 N.A. N.A. N.A. N.A. 53.8 59.2 N.A. N.A.
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 86.6 N.A. 20 N.A. N.A. N.A. N.A. 6.6 46.6 N.A. N.A.
P-Site Similarity: 100 N.A. 100 100 N.A. 100 93.3 N.A. 33.3 N.A. N.A. N.A. N.A. 26.6 80 N.A. N.A.
Percent
Protein Identity: 35.2 N.A. N.A. N.A. 31.4 N.A.
Protein Similarity: 53 N.A. N.A. N.A. 51.9 N.A.
P-Site Identity: 60 N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: 86.6 N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 10 20 0 20 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 20 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 80 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 10 0 20 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 10 70 0 0 0 0 0 0 80 10 10 80 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 20 20 0 0 0 0 0 0 0 10 % I
% Lys: 0 10 20 10 0 0 0 0 0 0 0 0 0 0 10 % K
% Leu: 0 10 0 0 0 60 50 0 0 0 0 0 20 100 30 % L
% Met: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 80 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 70 0 0 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 60 0 0 20 0 0 10 80 50 20 50 0 0 0 10 % S
% Thr: 10 0 0 30 10 0 0 10 0 0 10 0 0 0 0 % T
% Val: 10 0 0 10 0 0 20 0 0 0 0 0 0 0 40 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _