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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL3
All Species:
25.76
Human Site:
T622
Identified Species:
62.96
UniProt:
Q12788
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12788
NP_006444.2
808
89035
T622
R
L
D
D
H
A
L
T
G
A
S
D
S
R
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082569
888
97459
T705
R
L
D
D
R
A
L
T
G
A
S
D
S
R
V
Dog
Lupus familis
XP_547184
801
88352
T619
R
L
D
D
R
A
L
T
G
A
S
D
S
C
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4J7
801
88247
T622
Q
L
D
D
H
A
I
T
G
G
S
D
S
R
I
Rat
Rattus norvegicus
Q5U2W5
800
88353
T622
R
L
D
D
H
A
I
T
G
G
S
D
S
R
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506690
757
82561
R612
V
W
G
L
H
C
N
R
Q
D
N
Q
A
L
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610526
787
88518
T621
R
S
N
R
F
F
Y
T
G
G
A
D
S
K
L
Honey Bee
Apis mellifera
XP_001120493
781
87939
S631
K
N
E
K
T
I
I
S
G
G
S
D
S
L
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002319254
913
100555
T684
K
K
T
E
M
F
A
T
G
G
G
D
A
V
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05946
817
91013
S634
N
D
G
D
M
I
V
S
A
D
A
D
G
V
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
87.7
88.1
N.A.
88.3
88.2
N.A.
65.8
N.A.
N.A.
N.A.
N.A.
32.2
38.4
N.A.
N.A.
Protein Similarity:
100
N.A.
89.3
93.4
N.A.
94.1
93.5
N.A.
78
N.A.
N.A.
N.A.
N.A.
53.8
59.2
N.A.
N.A.
P-Site Identity:
100
N.A.
93.3
86.6
N.A.
73.3
80
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
33.3
26.6
N.A.
N.A.
P-Site Similarity:
100
N.A.
93.3
86.6
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
60
60
N.A.
N.A.
Percent
Protein Identity:
35.2
N.A.
N.A.
N.A.
31.4
N.A.
Protein Similarity:
53
N.A.
N.A.
N.A.
51.9
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
10
0
10
30
20
0
20
0
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
10
50
60
0
0
0
0
0
20
0
90
0
0
0
% D
% Glu:
0
0
10
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
20
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
20
0
0
0
0
0
80
50
10
0
10
0
0
% G
% His:
0
0
0
0
40
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
20
30
0
0
0
0
0
0
0
20
% I
% Lys:
20
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
50
0
10
0
0
30
0
0
0
0
0
0
20
20
% L
% Met:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
10
0
0
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% Q
% Arg:
50
0
0
10
20
0
0
10
0
0
0
0
0
40
0
% R
% Ser:
0
10
0
0
0
0
0
20
0
0
60
0
70
0
10
% S
% Thr:
0
0
10
0
10
0
0
70
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
0
20
40
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _