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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNMA1 All Species: 2.12
Human Site: T734 Identified Species: 4.67
UniProt: Q12791 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12791 NP_001154824.1 1236 137560 T734 R V R G N V D T L E R A F P L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta O18867 1151 128915 S677 R L E D E Q P S T L S P K K K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q08460 1209 134378 R733 N T S P K L M R H D P L L I P
Rat Rattus norvegicus Q62976 1209 134356 R734 N T S P K L M R H D P L L I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510131 822 92544 L350 E D E Q P S T L S P K K K Q R
Chicken Gallus gallus Q8AYS8 1137 127628 L665 E D E Q P S T L S P K K K Q R
Frog Xenopus laevis Q90ZC7 1196 134483 D707 P L L M T G N D Q I D N M D S
Zebra Danio Brachydanio rerio NP_001139072 1184 133307 L688 M M R H D P L L I P G N E Q I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q03720 1200 133083 T708 N V R R P N G T G N G T G G M
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q95V25 1140 129511 R668 C K N L A L F R R N T K H S T
Sea Urchin Strong. purpuratus XP_783726 1307 143907 H756 I Q H W V G P H Q K R R E S A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 93 N.A. N.A. 94 93.9 N.A. 62.1 87.8 84 84.3 N.A. 54.8 N.A. 51.2 49
Protein Similarity: 100 N.A. 93.1 N.A. N.A. 94.3 94.1 N.A. 63.7 89.5 88.1 88.3 N.A. 68.5 N.A. 64.8 63.5
P-Site Identity: 100 N.A. 6.6 N.A. N.A. 0 0 N.A. 0 0 0 6.6 N.A. 20 N.A. 0 6.6
P-Site Similarity: 100 N.A. 20 N.A. N.A. 13.3 13.3 N.A. 6.6 6.6 13.3 33.3 N.A. 26.6 N.A. 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 10 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 19 0 10 10 0 10 10 0 19 10 0 0 10 0 % D
% Glu: 19 0 28 0 10 0 0 0 0 10 0 0 19 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 10 0 19 10 0 10 0 19 0 10 10 0 % G
% His: 0 0 10 10 0 0 0 10 19 0 0 0 10 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 10 10 0 0 0 19 10 % I
% Lys: 0 10 0 0 19 0 0 0 0 10 19 28 28 10 10 % K
% Leu: 0 19 10 10 0 28 10 28 10 10 0 19 19 0 10 % L
% Met: 10 10 0 10 0 0 19 0 0 0 0 0 10 0 10 % M
% Asn: 28 0 10 0 10 10 10 0 0 19 0 19 0 0 0 % N
% Pro: 10 0 0 19 28 10 19 0 0 28 19 10 0 10 19 % P
% Gln: 0 10 0 19 0 10 0 0 19 0 0 0 0 28 0 % Q
% Arg: 19 0 28 10 0 0 0 28 10 0 19 10 0 0 19 % R
% Ser: 0 0 19 0 0 19 0 10 19 0 10 0 0 19 10 % S
% Thr: 0 19 0 0 10 0 19 19 10 0 10 10 0 0 10 % T
% Val: 0 19 0 0 10 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _