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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TWF1 All Species: 15.76
Human Site: Y42 Identified Species: 31.52
UniProt: Q12792 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12792 NP_002813.2 350 40283 Y42 E Q L V I G S Y S Q P S D S W
Chimpanzee Pan troglodytes XP_001165727 384 43939 Y76 E Q L V I G S Y S Q P S D S W
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_543726 350 40067 Y42 E K L V I G S Y S Q P S D S W
Cat Felis silvestris
Mouse Mus musculus Q91YR1 350 40061 C42 E Q L V V G S C S P P S D S W
Rat Rattus norvegicus Q5RJR2 350 40072 C42 E Q L V V G S C S P P S D S W
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508452 357 40765 S49 E Q L V V G S S S E P A E S W
Chicken Gallus gallus Q5ZM35 349 39817 H42 E Q L V L G A H K E L A R R W
Frog Xenopus laevis Q68F50 350 40436 C42 E Q L T V S A C E K P T R S W
Zebra Danio Brachydanio rerio Q6GMH3 347 39840 E42 L V L G A Y R E P R H S W D K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VFM9 343 39052 T42 E Q L S C G A T A E T K K D W
Honey Bee Apis mellifera XP_393653 350 39782 F42 E E L I P A A F S K P V N K W
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53250 332 37052 Q42 P D S T S V H Q T Q V A R S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.6 N.A. 97.7 N.A. 94.8 94.5 N.A. 89.9 66.8 79.7 63.1 N.A. 48.2 53.1 N.A. N.A.
Protein Similarity: 100 90.6 N.A. 99.1 N.A. 97.7 97.4 N.A. 96.3 86.8 91.1 82.5 N.A. 72.2 74 N.A. N.A.
P-Site Identity: 100 100 N.A. 93.3 N.A. 80 80 N.A. 66.6 40 40 13.3 N.A. 33.3 33.3 N.A. N.A.
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 93.3 73.3 66.6 20 N.A. 53.3 73.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 43.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 9 34 0 9 0 0 25 0 0 0 % A
% Cys: 0 0 0 0 9 0 0 25 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 42 17 0 % D
% Glu: 84 9 0 0 0 0 0 9 9 25 0 0 9 0 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 9 0 67 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 9 0 0 9 0 0 0 0 % H
% Ile: 0 0 0 9 25 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 9 17 0 9 9 9 9 % K
% Leu: 9 0 92 0 9 0 0 0 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 9 0 0 0 9 0 0 0 9 17 67 0 0 0 0 % P
% Gln: 0 67 0 0 0 0 0 9 0 34 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 9 0 0 25 9 0 % R
% Ser: 0 0 9 9 9 9 50 9 59 0 0 50 0 67 0 % S
% Thr: 0 0 0 17 0 0 0 9 9 0 9 9 0 0 0 % T
% Val: 0 9 0 59 34 9 0 0 0 0 9 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 84 % W
% Tyr: 0 0 0 0 0 9 0 25 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _