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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HYAL1
All Species:
24.24
Human Site:
T218
Identified Species:
59.26
UniProt:
Q12794
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12794
NP_009296.1
435
48368
T218
D
F
L
S
P
N
Y
T
G
Q
C
P
S
G
I
Chimpanzee
Pan troglodytes
XP_001168699
435
48279
T218
D
F
L
S
P
N
Y
T
G
Q
C
P
S
G
I
Rhesus Macaque
Macaca mulatta
XP_001102052
435
48438
T218
D
F
L
S
P
N
Y
T
G
Q
C
P
S
G
I
Dog
Lupus familis
XP_850767
504
55775
T287
D
F
L
S
P
N
Y
T
G
E
C
P
P
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZJ9
462
52019
T246
D
F
L
S
L
N
Y
T
G
Q
C
P
V
F
V
Rat
Rattus norvegicus
Q76HN1
449
50626
T233
D
F
L
S
P
N
Y
T
G
Q
C
S
L
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509131
442
50201
T227
D
F
K
N
P
N
Y
T
G
A
C
P
D
G
I
Chicken
Gallus gallus
XP_424356
436
48757
N218
N
F
S
D
P
L
Y
N
G
S
C
P
V
V
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001074140
486
55527
R221
G
Y
K
Q
H
P
F
R
Y
T
G
E
C
P
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Q08169
382
44241
D178
R
E
H
P
F
W
D
D
Q
R
V
E
Q
E
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
70
N.A.
69.6
72.1
N.A.
63.5
50.9
N.A.
44
N.A.
N.A.
25.9
N.A.
N.A.
Protein Similarity:
100
99.7
97.4
76.3
N.A.
80
82.4
N.A.
75.7
66.7
N.A.
57.8
N.A.
N.A.
45.5
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
73.3
80
N.A.
73.3
40
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
80
80
N.A.
80
46.6
N.A.
13.3
N.A.
N.A.
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
80
0
10
0
0
% C
% Asp:
70
0
0
10
0
0
10
10
0
0
0
0
10
0
0
% D
% Glu:
0
10
0
0
0
0
0
0
0
10
0
20
0
10
10
% E
% Phe:
0
80
0
0
10
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
10
0
0
0
0
0
0
0
80
0
10
0
0
50
0
% G
% His:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
60
% I
% Lys:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
60
0
10
10
0
0
0
0
0
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
10
0
70
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
10
70
10
0
0
0
0
0
70
10
10
0
% P
% Gln:
0
0
0
10
0
0
0
0
10
50
0
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% R
% Ser:
0
0
10
60
0
0
0
0
0
10
0
10
30
10
0
% S
% Thr:
0
0
0
0
0
0
0
70
0
10
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
20
10
10
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
80
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _