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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASPH All Species: 18.79
Human Site: Y90 Identified Species: 68.89
UniProt: Q12797 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12797 NP_004309.2 758 85863 Y90 V L G K L G I Y D A D G D G D
Chimpanzee Pan troglodytes XP_519784 1004 112407 Y336 V L G K L G I Y D A D G D G D
Rhesus Macaque Macaca mulatta XP_001090473 762 85964 Y94 V L G K L G I Y D A D G D G D
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BSY0 741 83024 Y99 V L G K L G V Y D A D G D G D
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_419224 885 100906 Y98 V L G K L G I Y D A D G D G D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_725525 785 89826 S90 P L S E S R F S K V F D G W V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798353 1318 147384 H143 A K A R P Q E H S S K D K K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.5 96.1 N.A. N.A. 81.6 N.A. N.A. N.A. 59.7 N.A. N.A. N.A. 31.9 N.A. N.A. 27
Protein Similarity: 100 75 96.8 N.A. N.A. 87.1 N.A. N.A. N.A. 69.7 N.A. N.A. N.A. 49.8 N.A. N.A. 39.3
P-Site Identity: 100 100 100 N.A. N.A. 93.3 N.A. N.A. N.A. 100 N.A. N.A. N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 100 100 N.A. N.A. 100 N.A. N.A. N.A. 100 N.A. N.A. N.A. 13.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 15 0 0 0 0 0 0 72 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 72 0 72 29 72 0 72 % D
% Glu: 0 0 0 15 0 0 15 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 15 0 0 0 15 0 0 0 0 % F
% Gly: 0 0 72 0 0 72 0 0 0 0 0 72 15 72 0 % G
% His: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 58 0 0 0 0 0 0 0 0 % I
% Lys: 0 15 0 72 0 0 0 0 15 0 15 0 15 15 15 % K
% Leu: 0 86 0 0 72 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 15 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 15 0 15 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 15 0 15 0 0 15 15 15 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 72 0 0 0 0 0 15 0 0 15 0 0 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % W
% Tyr: 0 0 0 0 0 0 0 72 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _