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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFEMP1
All Species:
23.94
Human Site:
S408
Identified Species:
58.52
UniProt:
Q12805
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12805
NP_001034437.1
493
54641
S408
R
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
Chimpanzee
Pan troglodytes
XP_001156698
623
68288
S538
R
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
Rhesus Macaque
Macaca mulatta
XP_001112450
421
46382
S336
R
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
Dog
Lupus familis
XP_531834
502
55193
S417
R
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPB5
493
54934
S408
R
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
Rat
Rattus norvegicus
O35568
493
54578
S408
R
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509946
458
51144
D374
S
D
R
S
V
P
S
D
I
F
Q
I
Q
A
T
Chicken
Gallus gallus
O73775
704
78120
T596
C
V
L
D
P
V
H
T
I
S
H
T
V
I
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O42182
681
74442
C564
C
Q
H
N
D
I
S
C
V
L
N
P
I
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O77469
728
79302
I588
G
S
F
K
C
H
S
I
D
C
P
T
N
Y
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.1
82.3
94.6
N.A.
94.5
93
N.A.
85.1
27.2
N.A.
26.5
N.A.
N.A.
N.A.
23.4
N.A.
Protein Similarity:
100
79.1
83.1
96.2
N.A.
96.7
96.5
N.A.
88.4
42.3
N.A.
41.2
N.A.
N.A.
N.A.
36.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
0
6.6
N.A.
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
0
26.6
N.A.
26.6
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
60
% A
% Cys:
20
0
0
0
10
0
0
10
0
10
0
0
0
0
0
% C
% Asp:
0
10
60
10
10
0
0
10
70
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
10
60
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
10
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
10
20
60
0
10
70
10
10
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
0
0
0
0
10
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
10
10
60
0
0
0
10
10
0
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
0
0
10
60
10
60
0
% Q
% Arg:
60
0
10
60
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
70
0
10
60
0
30
60
0
10
0
0
0
0
20
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
20
0
0
10
% T
% Val:
0
10
0
0
10
70
0
0
10
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _