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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB40B All Species: 21.82
Human Site: S253 Identified Species: 34.29
UniProt: Q12829 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q12829 NP_006813.1 278 30956 S253 S S T H K R S S L R K V K L V
Chimpanzee Pan troglodytes XP_001136104 278 31122 S253 S S T H K R S S L C K V K I V
Rhesus Macaque Macaca mulatta XP_001084457 278 31135 S253 S S T H K R S S L C K V K I V
Dog Lupus familis XP_850363 264 29147 G239 S S T H K R S G L R K V K A A
Cat Felis silvestris
Mouse Mus musculus Q8VHP8 278 31044 S253 N S S H K R N S F R K V R T I
Rat Rattus norvegicus P35286 203 22883 G179 K T G G R R S G N S S K P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519794 299 33388 K275 S G G G G G S K G N S L K R S
Chicken Gallus gallus Q5F470 207 23503 Q183 K L E G N S P Q G S N Q G V K
Frog Xenopus laevis NP_001087313 278 31377 S253 N N T N K R N S L K K A K I I
Zebra Danio Brachydanio rerio XP_002665253 287 32272 G262 S S A K K R N G T K K S K I I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572800 255 28642 S230 T T S Q C F N S L T Q S S K S
Honey Bee Apis mellifera XP_397266 294 32575 K257 S L G S H H R K L R F V G V G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P16976 208 23293 P184 Q A A L E R K P S N V V Q M K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28186 216 23816 T192 D S R A E P A T I K I S Q T D
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa P33723 203 22458 T179 R M G S S I A T N N T K A S V
Conservation
Percent
Protein Identity: 100 89.5 89.5 73.7 N.A. 92.8 34.1 N.A. 63.8 32 88.4 81.8 N.A. 59.7 60.8 N.A. N.A.
Protein Similarity: 100 93.5 93.5 78.7 N.A. 97.4 47.4 N.A. 78.2 45.6 95.3 89.1 N.A. 75.1 73.8 N.A. N.A.
P-Site Identity: 100 86.6 86.6 80 N.A. 53.3 13.3 N.A. 20 0 46.6 40 N.A. 13.3 26.6 N.A. N.A.
P-Site Similarity: 100 93.3 93.3 80 N.A. 86.6 26.6 N.A. 26.6 6.6 93.3 66.6 N.A. 46.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. 32.3 N.A. 35.9 N.A. 32.3
Protein Similarity: N.A. 47.1 N.A. 51.4 N.A. 46.4
P-Site Identity: N.A. 13.3 N.A. 6.6 N.A. 6.6
P-Site Similarity: N.A. 40 N.A. 46.6 N.A. 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 14 7 0 0 14 0 0 0 0 7 7 7 7 % A
% Cys: 0 0 0 0 7 0 0 0 0 14 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % D
% Glu: 0 0 7 0 14 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 7 0 0 7 0 7 0 0 0 0 % F
% Gly: 0 7 27 20 7 7 0 20 14 0 0 0 14 0 7 % G
% His: 0 0 0 34 7 7 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 0 0 7 0 7 0 0 27 20 % I
% Lys: 14 0 0 7 47 0 7 14 0 20 47 14 47 7 14 % K
% Leu: 0 14 0 7 0 0 0 0 47 0 0 7 0 7 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 0 0 0 7 0 % M
% Asn: 14 7 0 7 7 0 27 0 14 20 7 0 0 0 0 % N
% Pro: 0 0 0 0 0 7 7 7 0 0 0 0 7 0 0 % P
% Gln: 7 0 0 7 0 0 0 7 0 0 7 7 14 0 0 % Q
% Arg: 7 0 7 0 7 60 7 0 0 27 0 0 7 7 0 % R
% Ser: 47 47 14 14 7 7 40 40 7 14 14 20 7 14 20 % S
% Thr: 7 14 34 0 0 0 0 14 7 7 7 0 0 14 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 7 47 0 14 27 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _